KIR3DX1 killer cell immunoglobulin like receptor, three Ig domains X1 (pseudogene) [Homo sapiens (human)] - Gene

Summary

Official Symbol: KIR3DX1provided by HGNC
Official Full Name: killer cell immunoglobulin like receptor, three Ig domains X1 (pseudogene)provided by HGNC
Primary source: HGNC:HGNC:25043
See related: Ensembl:ENSG00000290933 AllianceGenome:HGNC:25043
Gene type: pseudo
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: LENG12; KIR3DL0
Summary: Predicted to be located in extracellular region. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression: Low expression observed in reference dataset See more
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Genomic context

Location:: 19q13.42

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	GRCh38.p14 (GCF_000001405.40)	19	NC_000019.10 (54532692..54545768)
RS_2023_10	current	T2T-CHM13v2.0 (GCF_009914755.1)	19	NC_060943.1 (57626038..57639114)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	19	NC_000019.9 (55043909..55057050)

Chromosome 19 - NC_000019.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: New genetic associations detected in a host response study to hepatitis B vaccine.

Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

REN93250 (e-PCR)
- UniSTS:418048

REN93251 (e-PCR)
- UniSTS:418049

REN93252 (e-PCR)
- UniSTS:418050

REN93253 (e-PCR)
- UniSTS:418051

REN93254 (e-PCR)
- UniSTS:418052

REN93255 (e-PCR)
- UniSTS:418053

REN93256 (e-PCR)
- UniSTS:418054

REN93257 (e-PCR)
- UniSTS:418055

REN93258 (e-PCR)
- UniSTS:418056

REN93259 (e-PCR)
- UniSTS:418057

REN93260 (e-PCR)
- UniSTS:418058

REN93261 (e-PCR)
- UniSTS:418059

REN93262 (e-PCR)
- UniSTS:418060

REN93263 (e-PCR)
- UniSTS:418061

REN93264 (e-PCR)
- UniSTS:418062

REN93265 (e-PCR)
- UniSTS:418063

REN93266 (e-PCR)
- UniSTS:418064

REN93267 (e-PCR)
- UniSTS:418065

REN93268 (e-PCR)
- UniSTS:418066

REN93269 (e-PCR)
- UniSTS:418067

D8S2278 (e-PCR)
- UniSTS:473906

sY3084 (e-PCR)
- UniSTS:515126

ECD05458 (e-PCR)
- UniSTS:286524

ECD12408 (e-PCR)
- UniSTS:293441

ECD04184 (e-PCR)
- UniSTS:285262

ECD22464 (e-PCR)
- UniSTS:303450

ECD05494 (e-PCR)
- UniSTS:286558

ECD16047 (e-PCR)
- UniSTS:297062

D1S1423 (e-PCR)
- UniSTS:149619

ECD04750 (e-PCR)
- UniSTS:285821

ECD15068 (e-PCR)
- UniSTS:296085

ECD14815 (e-PCR)
- UniSTS:295835

ECD05566 (e-PCR)
- UniSTS:286629

stSG606144 (e-PCR)
- UniSTS:448184

ECD23074 (e-PCR)
- UniSTS:304058

stSG606152 (e-PCR)
- UniSTS:448189

ECD06901 (e-PCR)
- UniSTS:287959

REN93211 (e-PCR)
- UniSTS:418009

REN93212 (e-PCR)
- UniSTS:418010

REN93213 (e-PCR)
- UniSTS:418011

REN93214 (e-PCR)
- UniSTS:418012

REN93215 (e-PCR)
- UniSTS:418013

REN93216 (e-PCR)
- UniSTS:418014

REN93217 (e-PCR)
- UniSTS:418015

REN93218 (e-PCR)
- UniSTS:418016

REN93219 (e-PCR)
- UniSTS:418017

REN93220 (e-PCR)
- UniSTS:418018

REN93221 (e-PCR)
- UniSTS:418019

REN93222 (e-PCR)
- UniSTS:418020

REN93223 (e-PCR)
- UniSTS:418021

REN93224 (e-PCR)
- UniSTS:418022

REN93225 (e-PCR)
- UniSTS:418023

REN93226 (e-PCR)
- UniSTS:418024

REN93227 (e-PCR)
- UniSTS:418025

REN93228 (e-PCR)
- UniSTS:418026

REN93229 (e-PCR)
- UniSTS:418027

REN93230 (e-PCR)
- UniSTS:418028

REN93231 (e-PCR)
- UniSTS:418029

REN93232 (e-PCR)
- UniSTS:418030

REN93233 (e-PCR)
- UniSTS:418031

REN93234 (e-PCR)
- UniSTS:418032

REN93235 (e-PCR)
- UniSTS:418033

ECD01765 (e-PCR)
- UniSTS:282866

REN93236 (e-PCR)
- UniSTS:418034

REN93237 (e-PCR)
- UniSTS:418035

REN93238 (e-PCR)
- UniSTS:418036

REN93239 (e-PCR)
- UniSTS:418037

REN93240 (e-PCR)
- UniSTS:418038

REN93241 (e-PCR)
- UniSTS:418039

REN93242 (e-PCR)
- UniSTS:418040

REN93243 (e-PCR)
- UniSTS:418041

REN93244 (e-PCR)
- UniSTS:418042

REN93245 (e-PCR)
- UniSTS:418043

REN93246 (e-PCR)
- UniSTS:418044

REN93247 (e-PCR)
- UniSTS:418045

REN93248 (e-PCR)
- UniSTS:418046

REN93249 (e-PCR)
- UniSTS:418047

Other Names

immunoglobulin-like receptor KIR3DL0
killer cell immunoglobulin-like receptor, three domains, X1
leukocyte receptor cluster (LRC) member 12

Gene Ontology Provided by GOA

Process	Evidence Code	Pubs
involved_in cell surface receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in immune response-regulating signaling pathway	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

NR_026716.2 RNA Sequence

Status: VALIDATED

Source sequence(s)

AK024467, BC033195, BC171827, DQ224421

Related

ENST00000610811.4
NR_104095.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AK024467, BC033195, BC171827
NR_104096.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AK024467, BC033195, BC171827, BC171832
NR_104097.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AK024467, BC033195, BC171838
NR_136268.1 RNA Sequence

Status: VALIDATED

Description

Transcript Variant: This variant (5) represents an alternate allele located on the reference alternate locus, ALT_REF_LOCI_7.

Source sequence(s)

AC009892, AC104536

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000019.10 Reference GRCh38.p14 Primary Assembly

Range

54532692..54545768

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GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

NW_003571054.1 Reference GRCh38.p14 ALT_REF_LOCI_1

Range

438900..451967

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GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_7

Genomic

NW_003571060.1 Reference GRCh38.p14 ALT_REF_LOCI_7

Range

437417..450484

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GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_9

Genomic

NT_187693.1 Reference GRCh38.p14 ALT_REF_LOCI_9

Range

515023..528164

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GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

NC_060943.1 Alternate T2T-CHM13v2.0

Range

57626038..57639114

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GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001047605.1: Suppressed sequence

Description

NM_001047605.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
NM_033206.1: Suppressed sequence

Description

NM_033206.1: This RefSeq was suppressed because the protein and transcript are insufficiently supported by other data and the transcript is a nonsense-mediated decay (NMD) candidate.