U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Herpud2 HERPUD family member 2 [ Mus musculus (house mouse) ]

Gene ID: 80517, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
Herpud2provided by MGI
Official Full Name
HERPUD family member 2provided by MGI
Primary source
MGI:MGI:1915393
See related
Ensembl:ENSMUSG00000008429 AllianceGenome:MGI:1915393
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5031400M07Rik
Summary
Acts upstream of or within spermatogenesis. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including adipose tissue; alimentary system; hemolymphoid system gland; nervous system; and reproductive system. Orthologous to human HERPUD2 (HERPUD family member 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 53.4), adrenal adult (RPKM 48.5) and 28 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
9 A4; 9 10.25 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (25012412..25063109, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (25108126..25151813, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA E130101E03 gene Neighboring gene transmembrane protein 126B pseudogene Neighboring gene STARR-seq mESC enhancer starr_23595 Neighboring gene STARR-seq mESC enhancer starr_23596 Neighboring gene predicted gene 29642 Neighboring gene STARR-seq mESC enhancer starr_23597 Neighboring gene RIKEN cDNA 9130004C02 gene Neighboring gene high mobility group box 2 pseudogene Neighboring gene septin 7

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species. Tonelli Gombalová Z, et al. J Comp Neurol, 2020 Oct 15. PMID 32212159
  2. Identification of differentially expressed genes in mouse spermatogenesis. Pang AL, et al. J Androl, 2003 Nov-Dec. PMID 14581517
  3. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
  4. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  5. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Spontaneous (1)  1 citation
  • Targeted (2) 
  • Endonuclease-mediated (1) 

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in endoplasmic reticulum unfolded protein response IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within response to unfolded protein IEA
Inferred from Electronic Annotation
more info
  
involved_in spermatogenesis IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020586.2 → NP_065611.1  homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein

    See identical proteins and their annotated locations for NP_065611.1

    Status: VALIDATED

    Source sequence(s)
    AC113082, CT025561
    Consensus CDS
    CCDS22934.1
    UniProtKB/Swiss-Prot
    Q8K2W2, Q9CSZ4, Q9D2D0, Q9JJC9
    Related
    ENSMUSP00000008573.8, ENSMUST00000008573.9
    Conserved Domains (2) summary
    cd01790
    Location:9 → 87
    Herp_N; Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain protein
    smart00213
    Location:10 → 87
    UBQ; Ubiquitin homologues

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    25012412..25063109 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006510706.4 → XP_006510769.1  homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein isoform X1

    Conserved Domains (1) summary
    cd17119
    Location:9 → 85
    Ubl_HERP2; ubiquitin-like (Ubl) domain found in homocysteine-inducible endoplasmic reticulum stress protein HERP2 and similar proteins
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9JJC9.1 GenPept UniProtKB/Swiss-Prot:Q9JJC9

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous