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Tex21 testis expressed gene 21 [ Mus musculus (house mouse) ]

Gene ID: 80384, updated on 8-Feb-2024

Summary

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Official Symbol
Tex21provided by MGI
Official Full Name
testis expressed gene 21provided by MGI
Primary source
MGI:MGI:1931131
See related
Ensembl:ENSMUSG00000021056 AllianceGenome:MGI:1931131
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
tsec-2; 4931406F04Rik; 4931412D23Rik; 4931421K24Rik
Summary
Orthologous to human TEX21P (testis expressed 21, pseudogene). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 15.7) See more
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Genomic context

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Location:
12 C3; 12 33.52 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (76245460..76293532, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (76198686..76246758, complement)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene spectrin repeat containing, nuclear envelope 2 Neighboring gene microRNA 5101 Neighboring gene STARR-seq mESC enhancer starr_32508 Neighboring gene estrogen receptor 2 (beta) Neighboring gene non-histone chromosomal protein HMG-14 pseudogene Neighboring gene STARR-positive B cell enhancer mm9_chr12:77297652-77297952 Neighboring gene STARR-seq mESC enhancer starr_32511 Neighboring gene STARR-seq mESC enhancer starr_32513 Neighboring gene STARR-positive B cell enhancer ABC_E4029 Neighboring gene methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase Neighboring gene predicted gene, 40444 Neighboring gene predicted gene, 40443

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Molecular cloning of a leucine zipper motif-containing novel cDNA specifically expressed in adult mouse testis. Chen L, et al. DNA Seq, 1998. PMID 10520738
  2. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Homology

Clone Names

  • MGC118241

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC80384
Names
testis expressed gene 11

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159532.1 → NP_001153004.1  uncharacterized protein LOC80384 isoform 2

    See identical proteins and their annotated locations for NP_001153004.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site at its 3'terminus which results in a distinct 3' UTR, compared to variant 1, and a protein (isoform 2) with a shorter and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    BC100432, CR520719
    Consensus CDS
    CCDS88353.1
    UniProtKB/TrEMBL
    Q497Q3, Q9D4K1
    Related
    ENSMUSP00000151515.2, ENSMUST00000218426.2
    Conserved Domains (1) summary
    COG1196
    Location:88 → 480
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  2. NM_019784.5 → NP_062758.3  uncharacterized protein LOC80384 isoform 1

    See identical proteins and their annotated locations for NP_062758.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1).
    Source sequence(s)
    AK016471, BC100432, BX638105
    Consensus CDS
    CCDS25989.1
    UniProtKB/TrEMBL
    Q9D4K1, Q9R0U9
    Related
    ENSMUSP00000021453.5, ENSMUST00000021453.6
    Conserved Domains (1) summary
    COG1196
    Location:88 → 480
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    76245460..76293532 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006516393.3 → XP_006516456.1  uncharacterized protein LOC80384 isoform X1

    UniProtKB/TrEMBL
    Q9D4K1
    Conserved Domains (2) summary
    COG1196
    Location:33 → 420
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR03185
    Location:13 → 136
    DNA_S_dndD; DNA sulfur modification protein DndD

  2. XM_006516394.2 → XP_006516457.1  uncharacterized protein LOC80384 isoform X2

    UniProtKB/TrEMBL
    Q9D4K1
    Conserved Domains (2) summary
    COG1196
    Location:87 → 454
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    PRK03918
    Location:78 → 214
    PRK03918; DNA double-strand break repair ATPase Rad50
Nucleotide Protein Strain
Heading Accession and Version

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