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Cttnbp2nl CTTNBP2 N-terminal like [ Mus musculus (house mouse) ]

Gene ID: 80281, updated on 5-Mar-2024

Summary

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Official Symbol
Cttnbp2nlprovided by MGI
Official Full Name
CTTNBP2 N-terminal likeprovided by MGI
Primary source
MGI:MGI:1933137
See related
Ensembl:ENSMUSG00000062127 AllianceGenome:MGI:1933137
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA1433
Summary
Predicted to enable protein phosphatase 2A binding activity. Acts upstream of or within protein dephosphorylation. Predicted to be located in cell projection; cytoplasm; and cytoskeleton. Predicted to be active in actin cytoskeleton. Is expressed in several structures, including alimentary system; axial musculature; orbito-sphenoid; urinary system; and vibrissa. Orthologous to human CTTNBP2NL (CTTNBP2 N-terminal like). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in lung adult (RPKM 8.8), CNS E11.5 (RPKM 6.0) and 27 other tissues See more
Orthologs
human all
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Genomic context

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Location:
3 F2.2; 3 45.88 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (104909231..104960462, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (105001915..105053146, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene wingless-type MMTV integration site family, member 2B Neighboring gene predicted gene, 46819 Neighboring gene uncharacterized LOC118568635 Neighboring gene predicted gene, 40116 Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:104855959-104856068 Neighboring gene RIKEN cDNA 4930564D02 gene Neighboring gene STARR-seq mESC enhancer starr_08630 Neighboring gene predicted gene, 40118 Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:104936010-104936231

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Genetic variants related to gap junctions and hormone secretion influence conception rates in cows. Sugimoto M, et al. Proc Natl Acad Sci U S A, 2013 Nov 26. PMID 24218568, Free PMC Article
  2. A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies. Breslow DK, et al. Nat Genet, 2018 Mar. PMID 29459677, Free PMC Article
  3. Phosphoproteomic analysis of the developing mouse brain. Ballif BA, et al. Mol Cell Proteomics, 2004 Nov. PMID 15345747
  4. Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Aug 31. PMID 14621295
  5. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC7720

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein phosphatase 2A binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein phosphatase 2A binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of transmembrane transport ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within negative regulation of transporter activity ISO
Inferred from Sequence Orthology
more info
  
involved_in protein dephosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within protein dephosphorylation IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within protein dephosphorylation ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
  
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
CTTNBP2 N-terminal-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163332.2 → NP_001156804.1  CTTNBP2 N-terminal-like protein

    See identical proteins and their annotated locations for NP_001156804.1

    Status: VALIDATED

    Source sequence(s)
    AC141889, AC166156
    Consensus CDS
    CCDS17707.1
    UniProtKB/Swiss-Prot
    Q6ZPR0, Q8BSV1, Q922L8, Q99LJ0
    Related
    ENSMUSP00000096359.3, ENSMUST00000098763.7
    Conserved Domains (3) summary
    PHA03247
    Location:482 → 638
    PHA03247; large tegument protein UL36; Provisional
    TIGR02168
    Location:100 → 292
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam09727
    Location:5 → 188
    CortBP2; Cortactin-binding protein-2

  2. NM_001163333.2 → NP_001156805.1  CTTNBP2 N-terminal-like protein

    See identical proteins and their annotated locations for NP_001156805.1

    Status: VALIDATED

    Source sequence(s)
    AC141889, AC166156
    Consensus CDS
    CCDS17707.1
    UniProtKB/Swiss-Prot
    Q6ZPR0, Q8BSV1, Q922L8, Q99LJ0
    Conserved Domains (3) summary
    PHA03247
    Location:482 → 638
    PHA03247; large tegument protein UL36; Provisional
    TIGR02168
    Location:100 → 292
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam09727
    Location:5 → 188
    CortBP2; Cortactin-binding protein-2

  3. NM_001411186.1 → NP_001398115.1  CTTNBP2 N-terminal-like protein

    Status: VALIDATED

    Source sequence(s)
    AC141889, AC166156
    UniProtKB/Swiss-Prot
    Q6ZPR0, Q8BSV1, Q922L8, Q99LJ0

  4. NM_001411188.1 → NP_001398117.1  CTTNBP2 N-terminal-like protein

    Status: VALIDATED

    Source sequence(s)
    AC141889, AC166156
    UniProtKB/Swiss-Prot
    Q6ZPR0, Q8BSV1, Q922L8, Q99LJ0

  5. NM_001411189.1 → NP_001398118.1  CTTNBP2 N-terminal-like protein

    Status: VALIDATED

    Source sequence(s)
    AC141889, AC166156
    UniProtKB/Swiss-Prot
    Q6ZPR0, Q8BSV1, Q922L8, Q99LJ0

  6. NM_001411190.1 → NP_001398119.1  CTTNBP2 N-terminal-like protein

    Status: VALIDATED

    Source sequence(s)
    AC141889, AC166156
    UniProtKB/Swiss-Prot
    Q6ZPR0, Q8BSV1, Q922L8, Q99LJ0

  7. NM_001411191.1 → NP_001398120.1  CTTNBP2 N-terminal-like protein

    Status: VALIDATED

    Source sequence(s)
    AC141889, AC166156
    UniProtKB/Swiss-Prot
    Q6ZPR0, Q8BSV1, Q922L8, Q99LJ0

  8. NM_001411192.1 → NP_001398121.1  CTTNBP2 N-terminal-like protein

    Status: VALIDATED

    Source sequence(s)
    AC141889, AC166156
    UniProtKB/Swiss-Prot
    Q6ZPR0, Q8BSV1, Q922L8, Q99LJ0

  9. NM_001411193.1 → NP_001398122.1  CTTNBP2 N-terminal-like protein

    Status: VALIDATED

    Source sequence(s)
    AC141889, AC166156
    UniProtKB/Swiss-Prot
    Q6ZPR0, Q8BSV1, Q922L8, Q99LJ0

  10. NM_030249.4 → NP_084525.1  CTTNBP2 N-terminal-like protein

    See identical proteins and their annotated locations for NP_084525.1

    Status: VALIDATED

    Source sequence(s)
    AC166156, AK029901
    Consensus CDS
    CCDS17707.1
    UniProtKB/Swiss-Prot
    Q6ZPR0, Q8BSV1, Q922L8, Q99LJ0
    Related
    ENSMUSP00000076751.6, ENSMUST00000077548.12
    Conserved Domains (3) summary
    PHA03247
    Location:482 → 638
    PHA03247; large tegument protein UL36; Provisional
    TIGR02168
    Location:100 → 292
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam09727
    Location:5 → 188
    CortBP2; Cortactin-binding protein-2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    104909231..104960462 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q99LJ0.1 GenPept UniProtKB/Swiss-Prot:Q99LJ0

Gene LinkOut

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