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C10orf95 chromosome 10 open reading frame 95 [ Homo sapiens (human) ]

Gene ID: 79946, updated on 5-Mar-2024

Summary

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Official Symbol
C10orf95provided by HGNC
Official Full Name
chromosome 10 open reading frame 95provided by HGNC
Primary source
HGNC:HGNC:25880
See related
Ensembl:ENSG00000120055 AllianceGenome:HGNC:25880
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in lung (RPKM 2.4), thyroid (RPKM 2.2) and 25 other tissues See more
Orthologs
all
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Genomic context

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Location:
10q24.32
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (102449837..102451543, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (103334824..103336530, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (104209594..104211300, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene CUE domain containing 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3935 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:104192697-104193332 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:104193333-104193966 Neighboring gene microRNA 146b Neighboring gene C10orf95 antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2760 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2761 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:104211267-104211949 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:104214138-104214726 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:104214727-104215314 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr10:104215315-104215904 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr10:104215905-104216492 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:104216493-104217081 Neighboring gene uncharacterized LOC124902493 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3937 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:104220868-104221551 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:104221552-104222234 Neighboring gene major facilitator superfamily domain containing 13A Neighboring gene ReSE screen-validated silencer GRCh37_chr10:104233222-104233665 Neighboring gene actin related protein 1A Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:104260453-104260953 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3938

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Nogo-B receptor is necessary for cellular dolichol biosynthesis and protein N-glycosylation. Harrison KD, et al. EMBO J, 2011 May 13. PMID 21572394, Free PMC Article
  2. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Eeles RA, et al. Nat Genet, 2013 Apr. PMID 23535732, Free PMC Article
  3. The DNA sequence and comparative analysis of human chromosome 10. Deloukas P, et al. Nature, 2004 May 27. PMID 15164054
  4. SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity. Shi P, et al. J Immunol, 2020 Jul 1. PMID 32393512
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • FLJ14280

General protein information

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Preferred Names
uncharacterized protein C10orf95

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001363580.1 → NP_001350509.1  uncharacterized protein C10orf95

    Status: VALIDATED

    Source sequence(s)
    AK024342, AL121928
    Consensus CDS
    CCDS91337.1
    UniProtKB/TrEMBL
    A0A1B0GTG0
    Related
    ENSP00000489684.1, ENST00000625129.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    102449837..102451543 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    103334824..103336530 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_024886.2: Suppressed sequence

    Description
    NM_024886.2: This RefSeq was removed because currently it is thought that it is annotated with an incorrect coding sequence.
Nucleotide Protein
Heading Accession and Version

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