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Zfp319 zinc finger protein 319 [ Mus musculus (house mouse) ]

Gene ID: 79233, updated on 5-Mar-2024

Summary

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Official Symbol
Zfp319provided by MGI
Official Full Name
zinc finger protein 319provided by MGI
Primary source
MGI:MGI:1890618
See related
Ensembl:ENSMUSG00000046556 AllianceGenome:MGI:1890618
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Znf319; mKIAA1388
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including central nervous system and genitourinary system. Orthologous to human ZNF319 (zinc finger protein 319). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thymus adult (RPKM 16.4), lung adult (RPKM 14.1) and 27 other tissues See more
Orthologs
human all
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Genomic context

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Location:
8 C5; 8 47.12 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (96052759..96058439, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (95326131..95331811, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:97769227-97769421 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:97771323-97771506 Neighboring gene STARR-positive B cell enhancer ABC_E3796 Neighboring gene cyclic nucleotide gated channel beta 1 Neighboring gene microtubule-associated protein 1 light chain 3 pseudogene copy 6 Neighboring gene sperm microtubule inner protein 8 Neighboring gene STARR-positive B cell enhancer ABC_E8259 Neighboring gene U6 snRNA biogenesis 1 Neighboring gene matrix metallopeptidase 15 Neighboring gene VISTA enhancer mm71 Neighboring gene STARR-positive B cell enhancer ABC_E245 Neighboring gene cilia and flagella associated protein 20

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Overexpression of a novel zinc-finger protein induces apoptosis in NIH3T3 fibroblasts. Laub F, et al. Genomics, 2000 Dec 15. PMID 11161788
  2. Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Feb 28. PMID 12693553
  3. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
  4. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  5. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • KIAA1388

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
zinc finger protein 319

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024467.4 → NP_077787.3  zinc finger protein 319

    See identical proteins and their annotated locations for NP_077787.3

    Status: VALIDATED

    Source sequence(s)
    AC165414
    Consensus CDS
    CCDS22559.1
    UniProtKB/Swiss-Prot
    Q9ERR8
    UniProtKB/TrEMBL
    Q8C7A0
    Related
    ENSMUSP00000053397.7, ENSMUST00000057717.8
    Conserved Domains (3) summary
    COG5048
    Location:88 → 531
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:203 → 223
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:499 → 524
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    96052759..96058439 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9ERR8.1 GenPept UniProtKB/Swiss-Prot:Q9ERR8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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