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Zc3h6 zinc finger CCCH type containing 6 [ Mus musculus (house mouse) ]

Gene ID: 78751, updated on 5-Mar-2024

Summary

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Official Symbol
Zc3h6provided by MGI
Official Full Name
zinc finger CCCH type containing 6provided by MGI
Primary source
MGI:MGI:1926001
See related
Ensembl:ENSMUSG00000042851 AllianceGenome:MGI:1926001
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Zc3hdc6; mKIAA2035; 4631426G04Rik; 4833425H18Rik
Summary
Predicted to enable metal ion binding activity. Predicted to be active in nucleus. Is expressed in early conceptus and genitourinary system. Orthologous to human ZC3H6 (zinc finger CCCH-type containing 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 2.2), cerebellum adult (RPKM 2.2) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
2 F1; 2 62.63 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (128809285..128860483)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (128967402..129018563)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene zinc finger CCCH type containing 8 Neighboring gene STARR-positive B cell enhancer ABC_E7861 Neighboring gene STARR-positive B cell enhancer ABC_E3403 Neighboring gene predicted gene 14028 Neighboring gene STARR-seq mESC enhancer starr_05655 Neighboring gene vinculin/alpha-catenin family member 1 Neighboring gene predicted gene, 54152 Neighboring gene STARR-seq mESC enhancer starr_05657 Neighboring gene tubulin tyrosine ligase Neighboring gene predicted gene, 46764

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Extensive molecular differences between anterior- and posterior-half-sclerotomes underlie somite polarity and spinal nerve segmentation. Hughes DS, et al. BMC Dev Biol, 2009 May 22. PMID 19463158, Free PMC Article
  2. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
  3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  4. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
  5. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Markers

Homology

Clone Names

  • KIAA2035

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in negative regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger CCCH domain-containing protein 6
Names
zinc finger CCCH type domain containing 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178404.3 → NP_848491.2  zinc finger CCCH domain-containing protein 6

    See identical proteins and their annotated locations for NP_848491.2

    Status: VALIDATED

    Source sequence(s)
    AL833780
    Consensus CDS
    CCDS50707.1
    UniProtKB/Swiss-Prot
    A2AP87, Q80UK3, Q8BYK8, Q8C1H1, Q9D604
    UniProtKB/TrEMBL
    A2AP88
    Related
    ENSMUSP00000105949.3, ENSMUST00000110320.9
    Conserved Domains (1) summary
    smart00356
    Location:301 → 325
    ZnF_C3H1; zinc finger

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    128809285..128860483
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011239850.2 → XP_011238152.1  zinc finger CCCH domain-containing protein 6 isoform X1

    UniProtKB/Swiss-Prot
    A2AP87, Q80UK3, Q8BYK8, Q8C1H1, Q9D604
    Conserved Domains (2) summary
    pfam15663
    Location:246 → 325
    zf-CCCH_3; Zinc-finger containing family
    pfam18345
    Location:282 → 300
    zf_CCCH_4; Zinc finger domain

  2. XM_011239851.1 → XP_011238153.1  zinc finger CCCH domain-containing protein 6 isoform X2

    Conserved Domains (2) summary
    pfam15663
    Location:12 → 91
    zf-CCCH_3; Zinc-finger containing family
    pfam18345
    Location:48 → 66
    zf_CCCH_4; Zinc finger domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BYK8.2 GenPept UniProtKB/Swiss-Prot:Q8BYK8

Gene LinkOut

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