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Troap trophinin associated protein [ Mus musculus (house mouse) ]

Gene ID: 78733, updated on 5-Mar-2024

Summary

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Official Symbol
Troapprovided by MGI
Official Full Name
trophinin associated proteinprovided by MGI
Primary source
MGI:MGI:1925983
See related
Ensembl:ENSMUSG00000032783 AllianceGenome:MGI:1925983
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
tastin; E130301L11Rik
Summary
Predicted to act upstream of or within cell adhesion. Predicted to be located in cytoplasm. Orthologous to human TROAP (trophinin associated protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in limb E14.5 (RPKM 9.0), CNS E11.5 (RPKM 8.9) and 20 other tissues See more
Orthologs
human all
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Genomic context

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Location:
15 F1; 15 55.8 cM
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (98972854..98981290)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (99074973..99083409)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene peripherin Neighboring gene predicted gene, 34284 Neighboring gene STARR-positive B cell enhancer ABC_E947 Neighboring gene microRNA 6960 Neighboring gene complement component 1, q subcomponent-like 4 Neighboring gene DnaJ heat shock protein family (Hsp40) member C22

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins. Hémono M, et al. BMC Biol, 2022 Jan 10. PMID 35012549, Free PMC Article
  2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  4. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
acts_upstream_of_or_within cell adhesion IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
tastin
Names
trophinin-assisting protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001162506.1 → NP_001155978.1  tastin

    See identical proteins and their annotated locations for NP_001155978.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    BC100405, BC145227
    Consensus CDS
    CCDS57008.1
    UniProtKB/Swiss-Prot
    B7ZNG4, Q497S4, Q8BWP3
    Related
    ENSMUSP00000155404.2, ENSMUST00000230054.2
    Conserved Domains (1) summary
    PHA03247
    Location:473 → 642
    PHA03247; large tegument protein UL36; Provisional

  2. NM_030159.1 → NP_084435.1  tastin

    See identical proteins and their annotated locations for NP_084435.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    BC080746, BC100405, BC145227
    Consensus CDS
    CCDS57008.1
    UniProtKB/Swiss-Prot
    B7ZNG4, Q497S4, Q8BWP3
    Related
    ENSMUSP00000035389.7, ENSMUST00000039665.8
    Conserved Domains (1) summary
    PHA03247
    Location:473 → 642
    PHA03247; large tegument protein UL36; Provisional

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    98972854..98981290
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030248822.1 → XP_030104682.1  tastin isoform X2

    Conserved Domains (1) summary
    PHA03247
    Location:166 → 335
    PHA03247; large tegument protein UL36; Provisional

  2. XM_036159638.1 → XP_036015531.1  tastin isoform X1

    Conserved Domains (1) summary
    PHA03247
    Location:227 → 396
    PHA03247; large tegument protein UL36; Provisional
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B7ZNG4.1 GenPept UniProtKB/Swiss-Prot:B7ZNG4

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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