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Ly6g6g lymphocyte antigen 6 family member G6G [ Mus musculus (house mouse) ]

Gene ID: 78725, updated on 8-Feb-2024

Summary

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Official Symbol
Ly6g6gprovided by MGI
Official Full Name
lymphocyte antigen 6 family member G6Gprovided by MGI
Primary source
MGI:MGI:1925975
See related
Ensembl:ENSMUSG00000101026 AllianceGenome:MGI:1925975
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable acetylcholine receptor inhibitor activity. Predicted to be active in plasma membrane. Predicted to be anchored component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in bladder adult (RPKM 2.1), kidney adult (RPKM 1.6) and 7 other tissues See more
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Genomic context

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See Ly6g6g in Genome Data Viewer
Location:
15 D3; 15 34.27 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (74642757..74656694, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (74770908..74778859, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene Ly6/neurotoxin 1 Neighboring gene lymphocyte antigen 6 family member D Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:74599639-74599822 Neighboring gene STARR-seq mESC enhancer starr_38995 Neighboring gene predicted gene, 33174 Neighboring gene lymphocyte antigen 6 family member K

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Organization, evolution and functions of the human and mouse Ly6/uPAR family genes. Loughner CL, et al. Hum Genomics, 2016 Apr 21. PMID 27098205, Free PMC Article
  2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • D730001G18Rik

Gene Ontology Provided by MGI

Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
lymphocyte antigen 6 complex, locus G6G

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001384153.1 → NP_001371082.1  lymphocyte antigen 6 complex, locus G6G isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AC139671
    UniProtKB/TrEMBL
    A0A087WQU7
    Related
    ENSMUSP00000140350.2, ENSMUST00000186014.2
    Conserved Domains (1) summary
    cd00117
    Location:21 → 91
    LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...

  2. NM_001384154.1 → NP_001371083.1  lymphocyte antigen 6 complex, locus G6G isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC139671
    UniProtKB/TrEMBL
    A0A087WRX0
    Related
    ENSMUSP00000140804.2, ENSMUST00000191407.2
    Conserved Domains (1) summary
    cl10471
    Location:24 → 58
    LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    74642757..74656694 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036159637.1 → XP_036015530.1  lymphocyte antigen 6 complex, locus G6G isoform X2

    Conserved Domains (1) summary
    cl10471
    Location:14 → 48
    LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...

  2. XM_036159636.1 → XP_036015529.1  lymphocyte antigen 6 complex, locus G6G isoform X1

    UniProtKB/TrEMBL
    A0A087WQU7
    Conserved Domains (1) summary
    cd00117
    Location:11 → 81
    LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_172433.2: Suppressed sequence

    Description
    NM_172433.2: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
Nucleotide Protein Strain
Heading Accession and Version

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