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Srbd1 S1 RNA binding domain 1 [ Mus musculus (house mouse) ]

Gene ID: 78586, updated on 5-Mar-2024

Summary

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Official Symbol
Srbd1provided by MGI
Official Full Name
S1 RNA binding domain 1provided by MGI
Primary source
MGI:MGI:1925836
See related
Ensembl:ENSMUSG00000024135 AllianceGenome:MGI:1925836
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D530025C17Rik
Summary
Predicted to enable mRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Is expressed in olfactory epithelium and thymus primordium. Orthologous to human SRBD1 (S1 RNA binding domain 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 1.0), CNS E14 (RPKM 0.7) and 25 other tissues See more
Orthologs
human all
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Genomic context

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Location:
17 E4; 17 56.51 cM
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (86292093..86452644, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (85984665..86145216, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_43474 Neighboring gene predicted gene 29418 Neighboring gene predicted gene 4718 Neighboring gene predicted gene, 30117 Neighboring gene predicted gene, 53966 Neighboring gene STARR-seq mESC enhancer starr_43477 Neighboring gene STARR-positive B cell enhancer ABC_E10975 Neighboring gene STARR-seq mESC enhancer starr_43480 Neighboring gene STARR-positive B cell enhancer ABC_E1511 Neighboring gene STARR-seq mESC enhancer starr_43481 Neighboring gene predicted gene 5817 Neighboring gene protein kinase C, epsilon Neighboring gene predicted gene, 52296

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells. Latos PA, et al. Nat Commun, 2015 Jul 24. PMID 26206133, Free PMC Article
  2. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  4. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC117756, MGC198776

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in nucleobase-containing compound metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
S1 RNA-binding domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_030133.3 → NP_084409.3  S1 RNA-binding domain-containing protein 1

    Status: VALIDATED

    Source sequence(s)
    AC154185, AC154542
    Consensus CDS
    CCDS50204.1
    UniProtKB/Swiss-Prot
    Q497V5
    UniProtKB/TrEMBL
    F8WGW3
    Related
    ENSMUSP00000092810.4, ENSMUST00000095187.4
    Conserved Domains (1) summary
    COG2183
    Location:205 → 978
    Tex; Transcriptional accessory protein Tex/SPT6 [Transcription]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    86292093..86452644 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011246728.1 → XP_011245030.1  S1 RNA-binding domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011245030.1

    UniProtKB/Swiss-Prot
    Q497V5
    Conserved Domains (2) summary
    COG2183
    Location:205 → 992
    Tex; Transcriptional accessory protein Tex/SPT6 [Transcription]
    pfam05793
    Location:9 → 186
    TFIIF_alpha; Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)

  2. XM_036160847.1 → XP_036016740.1  S1 RNA-binding domain-containing protein 1 isoform X6

    Conserved Domains (1) summary
    COG2183
    Location:21 → 601
    Tex; Transcriptional accessory protein Tex/SPT6 [Transcription]

  3. XM_011246731.4 → XP_011245033.1  S1 RNA-binding domain-containing protein 1 isoform X5

    Conserved Domains (1) summary
    COG2183
    Location:21 → 615
    Tex; Transcriptional accessory protein Tex/SPT6 [Transcription]

  4. XM_036160846.1 → XP_036016739.1  S1 RNA-binding domain-containing protein 1 isoform X2

    UniProtKB/Swiss-Prot
    Q497V5
    Conserved Domains (1) summary
    COG2183
    Location:205 → 822
    Tex; Transcriptional accessory protein Tex/SPT6 [Transcription]

  5. XM_017317728.1 → XP_017173217.1  S1 RNA-binding domain-containing protein 1 isoform X3

    Conserved Domains (2) summary
    COG2183
    Location:205 → 678
    Tex; Transcriptional accessory protein Tex/SPT6 [Transcription]
    pfam05793
    Location:9 → 186
    TFIIF_alpha; Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)

  6. XM_011246730.2 → XP_011245032.1  S1 RNA-binding domain-containing protein 1 isoform X4

    Conserved Domains (2) summary
    COG2183
    Location:205 → 619
    Tex; Transcriptional accessory protein Tex/SPT6 [Transcription]
    pfam05793
    Location:9 → 186
    TFIIF_alpha; Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)

RNA

  1. XR_385394.3 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q497V5.3 GenPept UniProtKB/Swiss-Prot:Q497V5

Gene LinkOut

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