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Mrpl9 mitochondrial ribosomal protein L9 [ Mus musculus (house mouse) ]

Gene ID: 78523, updated on 3-Apr-2024

Summary

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Official Symbol
Mrpl9provided by MGI
Official Full Name
mitochondrial ribosomal protein L9provided by MGI
Primary source
MGI:MGI:2137211
See related
Ensembl:ENSMUSG00000028140 AllianceGenome:MGI:2137211
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
L9mt; 8030480E20Rik; C330013D18Rik
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Orthologous to human MRPL9 (mitochondrial ribosomal protein L9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 22.6), liver E14 (RPKM 20.1) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
3 F2.1; 3 40.68 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (94350631..94355831)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (94443154..94448708)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700040D17 gene Neighboring gene STARR-positive B cell enhancer mm9_chr3:94216846-94217147 Neighboring gene tudor and KH domain containing protein Neighboring gene ornithine decarboxylase antizyme 3 Neighboring gene 40S ribosomal protein S2-like Neighboring gene STARR-positive B cell enhancer mm9_chr3:94260392-94260693 Neighboring gene regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 Neighboring gene CUGBP, Elav-like family member 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria. Suzuki T, et al. J Biol Chem, 2001 Jun 15. PMID 11279069
  2. Expression analysis of mammalian mitochondrial ribosomal protein genes. Cheong A, et al. Gene Expr Patterns, 2020 Dec. PMID 32987154, Free PMC Article
  3. Structure of the large ribosomal subunit from human mitochondria. Brown A, et al. Science, 2014 Nov 7. PMID 25278503, Free PMC Article
  4. Structure and Function of the Mitochondrial Ribosome. Greber BJ, et al. Annu Rev Biochem, 2016 Jun 2. PMID 27023846
  5. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, et al. Cell, 2003 Nov 26. PMID 14651853

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mitochondrial translation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane NAS
Non-traceable Author Statement
more info
 PubMed 
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
part_of mitochondrial large ribosomal subunit NAS
Non-traceable Author Statement
more info
 PubMed 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
large ribosomal subunit protein bL9m
Names
39S ribosomal protein L9, mitochondrial
MRP-L9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001419218.1 → NP_001406147.1  large ribosomal subunit protein bL9m isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC122808

  2. NM_030116.3 → NP_084392.1  large ribosomal subunit protein bL9m isoform 1

    See identical proteins and their annotated locations for NP_084392.1

    Status: VALIDATED

    Source sequence(s)
    AC122808
    Consensus CDS
    CCDS17593.1
    UniProtKB/Swiss-Prot
    Q3TSJ0, Q8BQZ2, Q99N94
    UniProtKB/TrEMBL
    Q14B21, Q8CA04
    Related
    ENSMUSP00000029786.8, ENSMUST00000029786.14
    Conserved Domains (2) summary
    PRK00137
    Location:92 → 222
    rplI; 50S ribosomal protein L9; Reviewed
    pfam01281
    Location:92 → 137
    Ribosomal_L9_N; Ribosomal protein L9, N-terminal domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    94350631..94355831
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q99N94.2 GenPept UniProtKB/Swiss-Prot:Q99N94

Gene LinkOut

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