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Nudt17 nudix hydrolase 17 [ Mus musculus (house mouse) ]

Gene ID: 78373, updated on 5-Mar-2024

Summary

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Official Symbol
Nudt17provided by MGI
Official Full Name
nudix hydrolase 17provided by MGI
Primary source
MGI:MGI:1925623
See related
Ensembl:ENSMUSG00000028100 AllianceGenome:MGI:1925623
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2410015C20Rik
Summary
Predicted to enable NADH pyrophosphatase activity. Predicted to be involved in NAD catabolic process; NADH metabolic process; and NADP catabolic process. Predicted to be active in peroxisome. Orthologous to human NUDT17 (nudix hydrolase 17). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in mammary gland adult (RPKM 3.2), thymus adult (RPKM 2.5) and 26 other tissues See more
Orthologs
human all
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Genomic context

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See Nudt17 in Genome Data Viewer
Location:
3 F2.1; 3 41.95 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (96613208..96616233, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (96705892..96708916, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L21, pseudogene 11 Neighboring gene STARR-positive B cell enhancer ABC_E6084 Neighboring gene STARR-seq mESC enhancer starr_08444 Neighboring gene ankyrin repeat domain 35 Neighboring gene protein inhibitor of activated STAT 3 Neighboring gene polymerase (RNA) III (DNA directed) polypeptide C Neighboring gene STARR-positive B cell enhancer ABC_E6085 Neighboring gene predicted gene, 22581 Neighboring gene ring finger protein 115

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  2. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  3. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  4. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article
  5. Functional annotation of a full-length mouse cDNA collection. Kawai J, et al. Nature, 2001 Feb 8. PMID 11217851

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables NADH pyrophosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in NAD catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in NADH metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in NADP catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in peroxisome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
nucleoside diphosphate-linked moiety X motif 17
Names
nudix (nucleoside diphosphate linked moiety X)-type motif 17
nudix motif 17
NP_001156397.1
NP_084370.1
XP_006502379.1
XP_006502380.1
XP_030108761.1
XP_030108762.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001162925.1 → NP_001156397.1  nucleoside diphosphate-linked moiety X motif 17 isoform 2

    See identical proteins and their annotated locations for NP_001156397.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an alternate in-frame coding exon compared to variant 1, resulting in a longer isoform (2) with a different internal protein segment compared to isoform 1.
    Source sequence(s)
    AC112261, AK019109, AK134929
    Consensus CDS
    CCDS51009.1
    UniProtKB/Swiss-Prot
    Q9CWD3
    Related
    ENSMUSP00000029742.6, ENSMUST00000029742.9
    Conserved Domains (1) summary
    cl00447
    Location:92 → 251
    Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...

  2. NM_030094.1 → NP_084370.1  nucleoside diphosphate-linked moiety X motif 17 isoform 1

    See identical proteins and their annotated locations for NP_084370.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the predominant transcript and encodes isoform 1.
    Source sequence(s)
    AK019109, AK134929
    Consensus CDS
    CCDS51008.1
    UniProtKB/Swiss-Prot
    Q14BX3, Q3URR9, Q9CWD3
    Related
    ENSMUSP00000129851.2, ENSMUST00000171249.6
    Conserved Domains (1) summary
    cl00447
    Location:92 → 234
    Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    96613208..96616233 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030252901.2 → XP_030108761.1  nucleoside diphosphate-linked moiety X motif 17 isoform X3

    Conserved Domains (1) summary
    cl00447
    Location:40 → 148
    Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...

  2. XM_030252902.2 → XP_030108762.1  nucleoside diphosphate-linked moiety X motif 17 isoform X3

    Conserved Domains (1) summary
    cl00447
    Location:40 → 148
    Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...

  3. XM_006502316.5 → XP_006502379.1  nucleoside diphosphate-linked moiety X motif 17 isoform X1

    Conserved Domains (1) summary
    cl00447
    Location:79 → 238
    Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...

  4. XM_006502317.5 → XP_006502380.1  nucleoside diphosphate-linked moiety X motif 17 isoform X2

    Conserved Domains (1) summary
    cl00447
    Location:79 → 221
    Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CWD3.1 GenPept UniProtKB/Swiss-Prot:Q9CWD3

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