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Ypel2 yippee like 2 [ Mus musculus (house mouse) ]

Gene ID: 77864, updated on 5-Mar-2024

Summary

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Official Symbol
Ypel2provided by MGI
Official Full Name
yippee like 2provided by MGI
Primary source
MGI:MGI:1925114
See related
Ensembl:ENSMUSG00000018427 AllianceGenome:MGI:1925114
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
6430570G24; E130113K08Rik
Summary
Predicted to enable metal ion binding activity. Predicted to be located in nucleus. Is expressed in forebrain and lens vesicle. Orthologous to human YPEL2 (yippee like 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 5.5), frontal lobe adult (RPKM 5.5) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
11 C; 11 51.82 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (86827251..86884629, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (86936425..86993805, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33742 Neighboring gene predicted gene, 38942 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:86706781-86707064 Neighboring gene predicted gene, 46290 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:86738694-86738847 Neighboring gene STARR-seq mESC enhancer starr_30286 Neighboring gene predicted gene, 51915 Neighboring gene predicted gene, 22387 Neighboring gene glycerophosphodiester phosphodiesterase domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. iSyTE: integrated Systems Tool for Eye gene discovery. Lachke SA, et al. Invest Ophthalmol Vis Sci, 2012 Mar. PMID 22323457, Free PMC Article
  2. Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species. Hosono K, et al. Gene, 2004 Sep 29. PMID 15556292
  3. YPEL5 protein of the YPEL gene family is involved in the cell cycle progression by interacting with two distinct proteins RanBPM and RanBP10. Hosono K, et al. Genomics, 2010 Aug. PMID 20580816
  4. Evidence Implicating CCNB1IP1, a RING Domain-Containing Protein Required for Meiotic Crossing Over in Mice, as an E3 SUMO Ligase. Strong ER, et al. Genes (Basel), 2010 Dec 2. PMID 21779533, Free PMC Article
  5. A genomic atlas of mouse hypothalamic development. Shimogori T, et al. Nat Neurosci, 2010 Jun. PMID 20436479, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein yippee-like 2
Names
ortholog of human yippee-like 2 YPEL2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005341.3 → NP_001005341.1  protein yippee-like 2

    See identical proteins and their annotated locations for NP_001005341.1

    Status: VALIDATED

    Source sequence(s)
    BB656522, BC121190, BY768876
    Consensus CDS
    CCDS25205.1
    UniProtKB/Swiss-Prot
    Q65Z95
    UniProtKB/TrEMBL
    Q0VA86
    Related
    ENSMUSP00000018571.5, ENSMUST00000018571.5
    Conserved Domains (1) summary
    cl13152
    Location:20 → 108
    RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    86827251..86884629 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011249316.4 → XP_011247618.1  protein yippee-like 2 isoform X1

    See identical proteins and their annotated locations for XP_011247618.1

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q65Z95.1 GenPept UniProtKB/Swiss-Prot:Q65Z95

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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