Lrrc42 leucine rich repeat containing 42 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Lrrc42provided by MGI
Official Full Name: leucine rich repeat containing 42provided by MGI
Primary source: MGI:MGI:1925059
See related: Ensembl:ENSMUSG00000028617 AllianceGenome:MGI:1925059
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: A930011F22Rik
Summary: Is expressed in cranium; jaw; tail dorsal root ganglion; and ventral grey horn. Orthologous to human LRRC42 (leucine rich repeat containing 42). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in thymus adult (RPKM 16.7), limb E14.5 (RPKM 15.6) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 4 C7; 4 50.18 cM

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	4	NC_000070.7 (107090711..107110730, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	4	NC_000070.6 (107233514..107253533, complement)

Chromosome 4 - NC_000070.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (1)
Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: leucine-rich repeat-containing protein 42

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_029985.2 → NP_084261.1 leucine-rich repeat-containing protein 42

See identical proteins and their annotated locations for NP_084261.1

Status: VALIDATED

Source sequence(s)

BC027203, BX632859, CJ174174

Consensus CDS

CCDS18434.1

UniProtKB/Swiss-Prot

Q3TE62, Q8R2U7, Q9CTP9

Related

ENSMUSP00000030360.5, ENSMUST00000030360.11

Conserved Domains (2) summary

cd00116
Location:167 → 272

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

sd00034
Location:150 → 174

LRR_AMN1; leucine-rich repeat [structural motif]