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Lcn12 lipocalin 12 [ Mus musculus (house mouse) ]

Gene ID: 77701, updated on 5-Mar-2024

Summary

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Official Symbol
Lcn12provided by MGI
Official Full Name
lipocalin 12provided by MGI
Primary source
MGI:MGI:1924951
See related
Ensembl:ENSMUSG00000026943 AllianceGenome:MGI:1924951
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9230102M18Rik
Summary
Predicted to enable retinoic acid binding activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human LCN12 (lipocalin 12). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward genital fat pad adult (RPKM 71.5) See more
Orthologs
human all
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Genomic context

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Location:
2 A3; 2 17.3 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (25380857..25384073, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (25490845..25494061, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene prostaglandin D2 synthase (brain) Neighboring gene predicted gene, 35287 Neighboring gene STARR-positive B cell enhancer ABC_E9193 Neighboring gene F-box and WD-40 domain protein 5 Neighboring gene complement component 8, gamma polypeptide Neighboring gene TNF receptor-associated factor 2 Neighboring gene cytochrome c oxidase subunit 7A2, mitochondrial pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Molecular evolution of epididymal lipocalin genes localized on mouse chromosome 2. Suzuki K, et al. Gene, 2004 Sep 15. PMID 15363845
  2. Update on the human and mouse lipocalin (LCN) gene family, including evidence the mouse Mup cluster is result of an "evolutionary bloom". Charkoftaki G, et al. Hum Genomics, 2019 Feb 19. PMID 30782214, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

General gene information

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Markers

Homology

Clone Names

  • MGC130532

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables retinoic acid binding ISO
Inferred from Sequence Orthology
more info
  
enables small molecule binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
epididymal-specific lipocalin-12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029958.1 → NP_084234.1  epididymal-specific lipocalin-12 precursor

    See identical proteins and their annotated locations for NP_084234.1

    Status: VALIDATED

    Source sequence(s)
    AY299493
    Consensus CDS
    CCDS15776.1
    UniProtKB/Swiss-Prot
    Q6JVL5
    UniProtKB/TrEMBL
    Q2TA58, Q9D265
    Related
    ENSMUSP00000028312.7, ENSMUST00000028312.13
    Conserved Domains (1) summary
    pfam00061
    Location:40 → 185
    Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    25380857..25384073 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011239211.1 → XP_011237513.1  epididymal-specific lipocalin-12 isoform X1

    Conserved Domains (1) summary
    cd19458
    Location:29 → 185
    lipocalin_12; Lipocalin 12

  2. XM_017319337.1 → XP_017174826.1  epididymal-specific lipocalin-12 isoform X2

    Conserved Domains (1) summary
    cl10502
    Location:2 → 149
    lipocalin_FABP; lipocalin/cytosolic fatty acid-binding protein family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6JVL5.1 GenPept UniProtKB/Swiss-Prot:Q6JVL5

Gene LinkOut

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