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Sun1 Sad1 and UNC84 domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 77053, updated on 16-Apr-2024

Summary

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Official Symbol
Sun1provided by MGI
Official Full Name
Sad1 and UNC84 domain containing 1provided by MGI
Primary source
MGI:MGI:1924303
See related
Ensembl:ENSMUSG00000036817 AllianceGenome:MGI:1924303
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Unc84a; mKIAA0810; 4632417G13Rik; 5730434D03Rik
Summary
Enables lamin binding activity. Involved in centrosome localization; meiotic attachment of telomere to nuclear envelope; and nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration. Acts upstream of or within homologous chromosome pairing at meiosis. Located in acrosomal membrane and nuclear envelope. Is integral component of nuclear inner membrane. Is expressed in intercostal muscle; spermatocyte; and spermatozoon. Orthologous to human SUN1 (Sad1 and UNC84 domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 24.4), bladder adult (RPKM 22.9) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
5 G2; 5 78.12 cM
Exon count:
28
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (139186313..139235594)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (139200564..139249839)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 6330403L08 gene Neighboring gene platelet derived growth factor, alpha Neighboring gene protein kinase, cAMP dependent regulatory, type I beta Neighboring gene STARR-positive B cell enhancer ABC_E1695 Neighboring gene STARR-seq mESC enhancer starr_14685 Neighboring gene STARR-positive B cell enhancer ABC_E10360 Neighboring gene dynein, axonemal assembly factor 5 Neighboring gene STARR-seq mESC enhancer starr_14686 Neighboring gene STARR-seq mESC enhancer starr_14687 Neighboring gene STARR-positive B cell enhancer ABC_E4802 Neighboring gene golgi to ER traffic protein 4 Neighboring gene STARR-positive B cell enhancer ABC_E2770 Neighboring gene STARR-positive B cell enhancer ABC_E6389 Neighboring gene STARR-positive B cell enhancer ABC_E9266 Neighboring gene ArfGAP with dual PH domains 1 Neighboring gene STARR-positive B cell enhancer ABC_E8825

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Nuclear SUN1 stabilizes endothelial cell junctions via microtubules to regulate blood vessel formation. Buglak DB, et al. Elife, 2023 Mar 29. PMID 36989130, Free PMC Article
  2. Requirement for Sun1 in the expression of meiotic reproductive genes and piRNA. Chi YH, et al. Development, 2009 Mar. PMID 19211677, Free PMC Article
  3. Sun1 forms immobile macromolecular assemblies at the nuclear envelope. Lu W, et al. Biochim Biophys Acta, 2008 Dec. PMID 18845190
  4. SUN1 is required for telomere attachment to nuclear envelope and gametogenesis in mice. Ding X, et al. Dev Cell, 2007 Jun. PMID 17543860
  5. Disrupting the LINC complex by AAV mediated gene transduction prevents progression of Lamin induced cardiomyopathy. Chai RJ, et al. Nat Commun, 2021 Aug 5. PMID 34354059, Free PMC Article

See all (83) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Nuclear SUN1 stabilizes endothelial cell junctions via microtubules to regulate blood vessel formation.
    Title: Nuclear SUN1 stabilizes endothelial cell junctions via microtubules to regulate blood vessel formation.
  2. The SUN2-nesprin-2 LINC complex and KIF20A function in the Golgi dispersal.
    Title: The SUN2-nesprin-2 LINC complex and KIF20A function in the Golgi dispersal.
  3. Disrupting the LINC complex by AAV mediated gene transduction prevents progression of Lamin induced cardiomyopathy.
    Title: Disrupting the LINC complex by AAV mediated gene transduction prevents progression of Lamin induced cardiomyopathy.
  4. The SUN1-SPDYA interaction plays an essential role in meiosis prophase I.
    Title: The SUN1-SPDYA interaction plays an essential role in meiosis prophase I.
  5. SUN1/2 Are Essential for RhoA/ROCK-Regulated Actomyosin Activity in Isolated Vascular Smooth Muscle Cells.
    Title: SUN1/2 Are Essential for RhoA/ROCK-Regulated Actomyosin Activity in Isolated Vascular Smooth Muscle Cells.
  6. Comparison of the miRNA profiles between wildtype and SUN1 null myotubes identified a cluster of miRNAs encoded by a non-translated retrotransposon-like one antisense (Rtl1as) transcript that are decreased in the WT myoblasts due to SUN1 inhibition of Drosha
    Title: The mammalian LINC complex component SUN1 regulates muscle regeneration by modulating drosha activity.
  7. Results provide evidence that SUN1 and KASH5 are essential factors in the regulation of meiotic resumption and spindle formation.
    Title: Depletion of the LINC complex disrupts cytoskeleton dynamics and meiotic resumption in mouse oocytes.
  8. A cell-type-specific role for Sun1 and Sun2 in nucleokinesis during cerebellar development, is reported.
    Title: Sun1 deficiency leads to cerebellar ataxia in mice.
  9. ablation of the kinase CDK2 alters the nuclear envelope in mouse spermatocytes, and that the proteins SUN1, KASH5 (also known as CCDC155) and lamin C2 show an abnormal cap-like distribution facing the centrosome.
    Title: CDK2 regulates nuclear envelope protein dynamics and telomere attachment in mouse meiotic prophase.
  10. our results clearly indicate that SUN1 and SUN2, at least partially, fulfill redundant meiotic functions
    Title: Analysis of meiosis in SUN1 deficient mice reveals a distinct role of SUN2 in mammalian meiotic LINC complex formation and function.
Submit: New GeneRIF Correction See all GeneRIFs (23)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • KIAA0810

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cytoskeleton-nuclear membrane anchor activity ISO
Inferred from Sequence Orthology
more info
  
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
enables lamin binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein-membrane adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in centrosome localization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within homologous chromosome pairing at meiosis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within meiotic attachment of telomere to nuclear envelope IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in meiotic attachment of telomere to nuclear envelope IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within meiotic cell cycle IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within nuclear envelope organization ISO
Inferred from Sequence Orthology
more info
  
involved_in nuclear matrix anchoring at nuclear membrane ISO
Inferred from Sequence Orthology
more info
  
involved_in nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within spermatogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chromosome, telomeric region IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
  
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
  
part_of meiotic nuclear membrane microtubule tethering complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of meiotic nuclear membrane microtubule tethering complex ISO
Inferred from Sequence Orthology
more info
  
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nuclear envelope IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nuclear envelope IDA
Inferred from Direct Assay
more info
 PubMed 
colocalizes_with nuclear envelope ISO
Inferred from Sequence Orthology
more info
  
located_in nuclear envelope ISO
Inferred from Sequence Orthology
more info
  
located_in nuclear envelope TAS
Traceable Author Statement
more info
  
located_in nuclear inner membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nuclear membrane ISO
Inferred from Sequence Orthology
more info
  
NOT located_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
SUN domain-containing protein 1
Names
protein unc-84 homolog A
sad1/unc-84 protein-like 1
unc-84 homolog A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001256115.1 → NP_001243044.1  SUN domain-containing protein 1 isoform 2

    See identical proteins and their annotated locations for NP_001243044.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The resulting isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AK036187, AV239459, CK389844
    Consensus CDS
    CCDS57395.1
    UniProtKB/Swiss-Prot
    Q9D666
    Related
    ENSMUSP00000106508.3, ENSMUST00000110884.9
    Conserved Domains (2) summary
    pfam07738
    Location:740 → 874
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam09387
    Location:73 → 378
    MRP; Mitochondrial RNA binding protein MRP

  2. NM_001256116.2 → NP_001243045.1  SUN domain-containing protein 1 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an in-frame exon in the coding region, compared to variant 1. The resulting isoform (3) is shorter than isoform 1.
    Source sequence(s)
    AC125065
    Consensus CDS
    CCDS57396.1
    UniProtKB/Swiss-Prot
    Q9D666
    Related
    ENSMUSP00000077756.7, ENSMUST00000078690.13
    Conserved Domains (2) summary
    pfam07738
    Location:713 → 847
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam09387
    Location:73 → 351
    MRP; Mitochondrial RNA binding protein MRP

  3. NM_001256117.1 → NP_001243046.1  SUN domain-containing protein 1 isoform 4

    See identical proteins and their annotated locations for NP_001243046.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks three consecutive exons in the coding region but maintains the reading frame, compared to variant 1. The resulting isoform (4) lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AK014585, AV239459, CK389844
    Consensus CDS
    CCDS57397.1
    UniProtKB/Swiss-Prot
    Q9D666
    Related
    ENSMUSP00000106507.3, ENSMUST00000110883.9
    Conserved Domains (2) summary
    pfam07738
    Location:654 → 788
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam09387
    Location:73 → 292
    MRP; Mitochondrial RNA binding protein MRP

  4. NM_001256118.1 → NP_001243047.1  SUN domain-containing protein 1 isoform 5

    See identical proteins and their annotated locations for NP_001243047.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) lacks four consecutive exons in the coding region but maintains the reading frame, compared to variant 1. The resulting isoform (5) lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AK160281, BQ551727, HQ402597
    Consensus CDS
    CCDS57398.1
    UniProtKB/Swiss-Prot
    Q9D666
    Related
    ENSMUSP00000106506.2, ENSMUST00000110882.8
    Conserved Domains (2) summary
    pfam07738
    Location:621 → 755
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam09387
    Location:73 → 259
    MRP; Mitochondrial RNA binding protein MRP

  5. NM_001359494.1 → NP_001346423.1  SUN domain-containing protein 1 isoform 6

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks an in-frame exon in the coding region and uses an alternate in-frame splice junction, compared to variant 1. The resulting isoform (6) is shorter than isoform 1.
    Source sequence(s)
    AC125065
    Conserved Domains (3) summary
    pfam07738
    Location:712 → 846
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam09387
    Location:73 → 351
    MRP; Mitochondrial RNA binding protein MRP
    cl25732
    Location:428 → 579
    SMC_N; RecF/RecN/SMC N terminal domain

  6. NM_001359496.1 → NP_001346425.1  SUN domain-containing protein 1 isoform 7

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) lacks two alternate in-frame exons, compared to variant 1. The resulting isoform (7) is shorter than isoform 1.
    Source sequence(s)
    AC125065
    Conserved Domains (3) summary
    pfam07738
    Location:676 → 810
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam09387
    Location:73 → 314
    MRP; Mitochondrial RNA binding protein MRP
    cl25732
    Location:385 → 564
    SMC_N; RecF/RecN/SMC N terminal domain

  7. NM_024451.2 → NP_077771.1  SUN domain-containing protein 1 isoform 1

    See identical proteins and their annotated locations for NP_077771.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) is the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AK160281, AK167686, BY036585
    Consensus CDS
    CCDS19804.1
    UniProtKB/Swiss-Prot
    D3Z0V9, Q3TIW3, Q3TV96, Q6B4H0, Q80SU8, Q8BZ99, Q99P23, Q9D666
    Related
    ENSMUSP00000056655.8, ENSMUST00000058716.14
    Conserved Domains (5) summary
    COG1196
    Location:486 → 665
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam07738
    Location:777 → 911
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam09387
    Location:63 → 415
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:709 → 734
    Sun2_CC2; SUN2 coiled coil domain 2
    cd21439
    Location:553 → 606
    SUN1_cc1; coiled-coil domain 1 of SUN domain-containing protein 1 and similar proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    139186313..139235594
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036165598.1 → XP_036021491.1  SUN domain-containing protein 1 isoform X22

    UniProtKB/TrEMBL
    Q3TSM1
    Related
    ENSMUSP00000098086.4, ENSMUST00000100517.10
    Conserved Domains (1) summary
    pfam09387
    Location:92 → 253
    MRP; Mitochondrial RNA binding protein MRP

  2. XM_017321156.3 → XP_017176645.1  SUN domain-containing protein 1 isoform X1

    Conserved Domains (4) summary
    pfam07738
    Location:815 → 949
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam07888
    Location:543 → 706
    CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    pfam09387
    Location:102 → 259
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:747 → 772
    Sun2_CC2; SUN2 coiled coil domain 2

  3. XM_017321157.3 → XP_017176646.1  SUN domain-containing protein 1 isoform X2

    Conserved Domains (4) summary
    pfam07738
    Location:814 → 948
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam07888
    Location:543 → 705
    CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    pfam09387
    Location:102 → 259
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:746 → 771
    Sun2_CC2; SUN2 coiled coil domain 2

  4. XM_036165596.1 → XP_036021489.1  SUN domain-containing protein 1 isoform X8

    Conserved Domains (4) summary
    pfam07738
    Location:777 → 911
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam09387
    Location:92 → 416
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:709 → 734
    Sun2_CC2; SUN2 coiled coil domain 2
    cd21439
    Location:554 → 605
    SUN1_cc1; coiled-coil domain 1 of SUN domain-containing protein 1 and similar proteins

  5. XM_017321162.3 → XP_017176651.1  SUN domain-containing protein 1 isoform X6

    Conserved Domains (4) summary
    pfam07738
    Location:778 → 912
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam07888
    Location:506 → 669
    CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    pfam09387
    Location:102 → 416
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:710 → 735
    Sun2_CC2; SUN2 coiled coil domain 2

  6. XM_017321164.3 → XP_017176653.1  SUN domain-containing protein 1 isoform X10

    Conserved Domains (4) summary
    pfam07738
    Location:756 → 890
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam07888
    Location:484 → 647
    CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    pfam09387
    Location:102 → 394
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:688 → 713
    Sun2_CC2; SUN2 coiled coil domain 2

  7. XM_030254889.2 → XP_030110749.1  SUN domain-containing protein 1 isoform X3

    Conserved Domains (4) summary
    pfam07738
    Location:805 → 939
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam07888
    Location:534 → 696
    CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    pfam09387
    Location:102 → 250
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:737 → 762
    Sun2_CC2; SUN2 coiled coil domain 2

  8. XM_017321165.3 → XP_017176654.1  SUN domain-containing protein 1 isoform X11

    Conserved Domains (4) summary
    pfam07738
    Location:751 → 885
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam07888
    Location:479 → 642
    CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    pfam09387
    Location:102 → 389
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:683 → 708
    Sun2_CC2; SUN2 coiled coil domain 2

  9. XM_017321168.3 → XP_017176657.1  SUN domain-containing protein 1 isoform X13

    Conserved Domains (4) summary
    pfam07738
    Location:714 → 848
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam07888
    Location:442 → 605
    CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    pfam09387
    Location:102 → 352
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:646 → 671
    Sun2_CC2; SUN2 coiled coil domain 2

  10. XM_017321163.3 → XP_017176652.1  SUN domain-containing protein 1 isoform X9

    Conserved Domains (4) summary
    pfam07738
    Location:768 → 902
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam07888
    Location:497 → 659
    CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    pfam09387
    Location:102 → 407
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:700 → 725
    Sun2_CC2; SUN2 coiled coil domain 2

  11. XM_030254894.2 → XP_030110754.1  SUN domain-containing protein 1 isoform X16

    Conserved Domains (4) summary
    pfam07738
    Location:691 → 825
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam07888
    Location:420 → 582
    CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    pfam09387
    Location:102 → 330
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:623 → 648
    Sun2_CC2; SUN2 coiled coil domain 2

  12. XM_030254890.2 → XP_030110750.1  SUN domain-containing protein 1 isoform X12

    Conserved Domains (4) summary
    pfam07738
    Location:747 → 881
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam07888
    Location:475 → 638
    CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    pfam09387
    Location:102 → 385
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:679 → 704
    Sun2_CC2; SUN2 coiled coil domain 2

  13. XM_017321170.3 → XP_017176659.1  SUN domain-containing protein 1 isoform X15

    Conserved Domains (4) summary
    pfam07738
    Location:692 → 826
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam07888
    Location:420 → 583
    CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    pfam09387
    Location:102 → 330
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:624 → 649
    Sun2_CC2; SUN2 coiled coil domain 2

  14. XM_017321171.3 → XP_017176660.1  SUN domain-containing protein 1 isoform X18

    Conserved Domains (4) summary
    pfam07738
    Location:659 → 793
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam07888
    Location:387 → 550
    CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    pfam09387
    Location:102 → 297
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:591 → 616
    Sun2_CC2; SUN2 coiled coil domain 2

  15. XM_017321169.3 → XP_017176658.1  SUN domain-containing protein 1 isoform X14

    Conserved Domains (4) summary
    pfam07738
    Location:704 → 838
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam07888
    Location:433 → 595
    CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    pfam09387
    Location:102 → 343
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:636 → 661
    Sun2_CC2; SUN2 coiled coil domain 2

  16. XM_036165597.1 → XP_036021490.1  SUN domain-containing protein 1 isoform X17

    Conserved Domains (4) summary
    pfam07738
    Location:682 → 816
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam09387
    Location:92 → 321
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:614 → 639
    Sun2_CC2; SUN2 coiled coil domain 2
    cd21439
    Location:459 → 510
    SUN1_cc1; coiled-coil domain 1 of SUN domain-containing protein 1 and similar proteins

  17. XM_006504767.4 → XP_006504830.1  SUN domain-containing protein 1 isoform X19

    Conserved Domains (4) summary
    pfam07738
    Location:650 → 784
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam07888
    Location:378 → 541
    CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    pfam09387
    Location:102 → 288
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:582 → 607
    Sun2_CC2; SUN2 coiled coil domain 2

  18. XM_036165595.1 → XP_036021488.1  SUN domain-containing protein 1 isoform X7

    UniProtKB/Swiss-Prot
    D3Z0V9, Q3TIW3, Q3TV96, Q6B4H0, Q80SU8, Q8BZ99, Q99P23, Q9D666
    Conserved Domains (5) summary
    COG1196
    Location:486 → 665
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam07738
    Location:777 → 911
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam09387
    Location:63 → 415
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:709 → 734
    Sun2_CC2; SUN2 coiled coil domain 2
    cd21439
    Location:553 → 606
    SUN1_cc1; coiled-coil domain 1 of SUN domain-containing protein 1 and similar proteins

  19. XM_017321160.2 → XP_017176649.1  SUN domain-containing protein 1 isoform X5

    Conserved Domains (4) summary
    pfam07738
    Location:786 → 920
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam07888
    Location:514 → 677
    CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    pfam09387
    Location:73 → 230
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:718 → 743
    Sun2_CC2; SUN2 coiled coil domain 2

  20. XM_017321159.2 → XP_017176648.1  SUN domain-containing protein 1 isoform X5

    Conserved Domains (4) summary
    pfam07738
    Location:786 → 920
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam07888
    Location:514 → 677
    CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    pfam09387
    Location:73 → 230
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:718 → 743
    Sun2_CC2; SUN2 coiled coil domain 2

  21. XM_017321161.2 → XP_017176650.1  SUN domain-containing protein 1 isoform X5

    Conserved Domains (4) summary
    pfam07738
    Location:786 → 920
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam07888
    Location:514 → 677
    CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    pfam09387
    Location:73 → 230
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:718 → 743
    Sun2_CC2; SUN2 coiled coil domain 2

  22. XM_030254895.2 → XP_030110755.1  SUN domain-containing protein 1 isoform X20

    Conserved Domains (4) summary
    pfam07738
    Location:629 → 763
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam07888
    Location:358 → 520
    CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    pfam09387
    Location:82 → 268
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:561 → 586
    Sun2_CC2; SUN2 coiled coil domain 2

  23. XM_030254897.2 → XP_030110757.1  SUN domain-containing protein 1 isoform X21

    Conserved Domains (4) summary
    pfam07738
    Location:620 → 754
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam07888
    Location:349 → 511
    CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    pfam09387
    Location:73 → 259
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:552 → 577
    Sun2_CC2; SUN2 coiled coil domain 2

  24. XM_017321158.1 → XP_017176647.1  SUN domain-containing protein 1 isoform X4

    Conserved Domains (4) summary
    pfam07738
    Location:795 → 929
    Sad1_UNC; Sad1 / UNC-like C-terminal
    pfam07888
    Location:523 → 686
    CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    pfam09387
    Location:82 → 239
    MRP; Mitochondrial RNA binding protein MRP
    pfam18580
    Location:727 → 752
    Sun2_CC2; SUN2 coiled coil domain 2
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D666.2 GenPept UniProtKB/Swiss-Prot:Q9D666

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