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Fbxw27 F-box and WD-40 domain protein 27 [ Mus musculus (house mouse) ]

Gene ID: 76998, updated on 8-Feb-2024

Summary

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Official Symbol
Fbxw27provided by MGI
Official Full Name
F-box and WD-40 domain protein 27provided by MGI
Primary source
MGI:MGI:1924248
See related
Ensembl:ENSMUSG00000104614 AllianceGenome:MGI:1924248
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700124P09Rik
Expression
Biased expression in testis adult (RPKM 3.9), bladder adult (RPKM 2.6) and 1 other tissue See more
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Genomic context

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Location:
9 F2; 9 59.74 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (109595045..109620484, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (109765977..109790660, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene F-box and WD-40 domain protein 18 Neighboring gene F-box and WD-40 domain protein 26 Neighboring gene predicted gene, 40579 Neighboring gene predicted gene, 51691 Neighboring gene serine peptidase inhibitor, Kazal type 8 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo. Evsikov AV, et al. Genes Dev, 2006 Oct 1. PMID 17015433, Free PMC Article
  2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
F-box and WD-40 domain protein 27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001303003.1 → NP_001289932.1  F-box and WD-40 domain protein 27 isoform 1

    See identical proteins and their annotated locations for NP_001289932.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK007274, BB702760, CJ082096, CO804891, DV663185
    UniProtKB/TrEMBL
    A0A1D5RLF0
    Related
    ENSMUSP00000148340.2, ENSMUST00000212725.2
    Conserved Domains (1) summary
    pfam12937
    Location:5 → 48
    F-box-like; F-box-like

  2. NM_001303004.1 → NP_001289933.1  F-box and WD-40 domain protein 27 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks four consecutive exons in the coding region, which results in a frameshift compared to variant 1. The encoded isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AK007274, CJ082096, CO804891, DV663185
    Consensus CDS
    CCDS85731.1
    UniProtKB/TrEMBL
    A0A1D5RLI0
    Related
    ENSMUSP00000148376.2, ENSMUST00000197125.3
    Conserved Domains (1) summary
    pfam12937
    Location:5 → 48
    F-box-like; F-box-like

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    109595045..109620484 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003084806.5 → XP_003084854.1  F-box and WD-40 domain protein 27 isoform X2

    UniProtKB/TrEMBL
    A0A1D5RLF0

  2. XM_001481022.6 → XP_001481072.1  F-box and WD-40 domain protein 27 isoform X1

    UniProtKB/TrEMBL
    A0A1D5RMD3
    Related
    ENSMUSP00000148730.2, ENSMUST00000199430.5
    Conserved Domains (1) summary
    pfam12937
    Location:5 → 46
    F-box-like
Nucleotide Protein Strain
Heading Accession and Version

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