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Rps9 ribosomal protein S9 [ Mus musculus (house mouse) ]

Gene ID: 76846, updated on 11-Apr-2024

Summary

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Official Symbol
Rps9provided by MGI
Official Full Name
ribosomal protein S9provided by MGI
Primary source
MGI:MGI:1924096
See related
Ensembl:ENSMUSG00000006333 AllianceGenome:MGI:1924096
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
3010033P07Rik
Summary
Predicted to enable rRNA binding activity and translation regulator activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in positive regulation of cell population proliferation; positive regulation of translational fidelity; and translation. Is active in synapse. Is expressed in several structures, including cerebral cortex; diaphragm; eye; genitourinary system; and soleus. Orthologous to human RPS9 (ribosomal protein S9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 388.6), liver E14 (RPKM 316.7) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
7 A1; 7 2.13 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (3707035..3709896)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (3703954..3706897)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene membrane bound O-acyltransferase domain containing 7 Neighboring gene tRNA splicing endonuclease subunit 34 Neighboring gene STARR-positive B cell enhancer ABC_E2812 Neighboring gene paired Ig-like receptor B Neighboring gene STARR-positive B cell enhancer mm9_chr7:3672088-3672388 Neighboring gene paired-Ig-like receptor A1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Error-prone protein synthesis recapitulates early symptoms of Alzheimer disease in aging mice. Brilkova M, et al. Cell Rep, 2022 Sep 27. PMID 36170830
  2. Premature aging in mice with error-prone protein synthesis. Shcherbakov D, et al. Sci Adv, 2022 Mar 4. PMID 35235349, Free PMC Article
  3. Global Hypertranscription in the Mouse Embryonic Germline. Percharde M, et al. Cell Rep, 2017 Jun 6. PMID 28591571, Free PMC Article
  4. The FgfrL1 receptor is required for development of slow muscle fibers. Amann R, et al. Dev Biol, 2014 Oct 15. PMID 25172430
  5. The unfolded protein response contributes to preimplantation mouse embryo death in the DDK syndrome. Hao L, et al. Biol Reprod, 2009 May. PMID 19129515, Free PMC Article

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC4138

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables 5.8S rRNA binding ISO
Inferred from Sequence Orthology
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables rRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
  
enables translation regulator activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in positive regulation of cell population proliferation ISO
Inferred from Sequence Orthology
more info
  
involved_in ribosomal small subunit biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosomal small subunit biogenesis ISO
Inferred from Sequence Orthology
more info
  
involved_in translation ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm NAS
Non-traceable Author Statement
more info
 PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
  
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
  
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic small ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
part_of cytosolic small ribosomal subunit NAS
Non-traceable Author Statement
more info
 PubMed 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
is_active_in postsynapse NAS
Non-traceable Author Statement
more info
 PubMed 
part_of ribonucleoprotein complex ISO
Inferred from Sequence Orthology
more info
  
is_active_in ribosome NAS
Non-traceable Author Statement
more info
 PubMed 
part_of small ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  
part_of small-subunit processome ISO
Inferred from Sequence Orthology
more info
  
is_active_in synapse EXP
Inferred from Experiment
more info
 PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
small ribosomal subunit protein uS4
Names
40S ribosomal protein S9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001419057.1 → NP_001405986.1  small ribosomal subunit protein uS4 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC171680

  2. NM_001419058.1 → NP_001405987.1  small ribosomal subunit protein uS4 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC171680

  3. NM_001419059.1 → NP_001405988.1  small ribosomal subunit protein uS4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC171680
    UniProtKB/Swiss-Prot
    Q3UBF1, Q6ZWN5, Q8K2D1
    Related
    ENSMUSP00000104265.2, ENSMUST00000108625.8

  4. NM_001419060.1 → NP_001405989.1  small ribosomal subunit protein uS4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC171680
    UniProtKB/Swiss-Prot
    Q3UBF1, Q6ZWN5, Q8K2D1

  5. NM_029767.3 → NP_084043.1  small ribosomal subunit protein uS4 isoform 1

    See identical proteins and their annotated locations for NP_084043.1

    Status: VALIDATED

    Source sequence(s)
    AC171680
    Consensus CDS
    CCDS20726.1
    UniProtKB/Swiss-Prot
    Q3UBF1, Q6ZWN5, Q8K2D1
    Related
    ENSMUSP00000006496.9, ENSMUST00000006496.15
    Conserved Domains (1) summary
    PTZ00155
    Location:11 → 177
    PTZ00155; 40S ribosomal protein S9; Provisional

RNA

  1. NR_185013.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC171680
    Related
    ENSMUST00000146927.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    3707035..3709896
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6ZWN5.3 GenPept UniProtKB/Swiss-Prot:Q6ZWN5

Gene LinkOut

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