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Armc6 armadillo repeat containing 6 [ Mus musculus (house mouse) ]

Gene ID: 76813, updated on 5-Mar-2024

Summary

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Official Symbol
Armc6provided by MGI
Official Full Name
armadillo repeat containing 6provided by MGI
Primary source
MGI:MGI:1924063
See related
Ensembl:ENSMUSG00000002343 AllianceGenome:MGI:1924063
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2410153K17Rik
Summary
Acts upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in cytosol. Orthologous to human ARMC6 (armadillo repeat containing 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E18 (RPKM 25.6), whole brain E14.5 (RPKM 18.6) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
8 B3.3; 8 34.15 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (70672822..70687099, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (70220172..70234446, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E10504 Neighboring gene transmembrane protein 161A Neighboring gene solute carrier family 25, member 42 Neighboring gene STARR-positive B cell enhancer ABC_E1103 Neighboring gene STARR-positive B cell enhancer ABC_E8239 Neighboring gene SURP and G patch domain containing 2 Neighboring gene predicted gene, 38427 Neighboring gene homer scaffolding protein 3 Neighboring gene DEAD box helicase 49

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. SF4 and SFRS14, two related putative splicing factors on human chromosome 19p13.11. Sampson ND, et al. Gene, 2003 Feb 13. PMID 12594045
  2. Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Nagamachi A, et al. Cancer Cell, 2013 Sep 9. PMID 24029230
  3. Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies. Murtaza N, et al. Cell Rep, 2022 Nov 22. PMID 36417873
  4. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Zhang T, et al. Sci Rep, 2017 Apr 5. PMID 28378742, Free PMC Article
  5. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC67564

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in hematopoietic progenitor cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within hematopoietic progenitor cell differentiation IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
armadillo repeat-containing protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133972.2 → NP_598733.2  armadillo repeat-containing protein 6

    See identical proteins and their annotated locations for NP_598733.2

    Status: PROVISIONAL

    Source sequence(s)
    BC043070
    Consensus CDS
    CCDS40371.1
    UniProtKB/Swiss-Prot
    Q8BNU0, Q8C4P5, Q8C7S1, Q8K2S7, Q99JQ2, Q9CWE4
    Related
    ENSMUSP00000019679.6, ENSMUST00000019679.12
    Conserved Domains (2) summary
    smart00185
    Location:184 → 226
    ARM; Armadillo/beta-catenin-like repeats
    sd00043
    Location:146 → 180
    ARM; armadillo repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    70672822..70687099 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011242332.4 → XP_011240634.1  armadillo repeat-containing protein 6 isoform X1

    See identical proteins and their annotated locations for XP_011240634.1

    Conserved Domains (2) summary
    smart00185
    Location:184 → 226
    ARM; Armadillo/beta-catenin-like repeats
    sd00043
    Location:146 → 180
    ARM; armadillo repeat [structural motif]

  2. XM_030243842.1 → XP_030099702.1  armadillo repeat-containing protein 6 isoform X2

    UniProtKB/Swiss-Prot
    Q8BNU0, Q8C4P5, Q8C7S1, Q8K2S7, Q99JQ2, Q9CWE4
    Conserved Domains (2) summary
    smart00185
    Location:184 → 226
    ARM; Armadillo/beta-catenin-like repeats
    sd00043
    Location:146 → 180
    ARM; armadillo repeat [structural motif]

  3. XM_030243841.2 → XP_030099701.1  armadillo repeat-containing protein 6 isoform X2

    UniProtKB/Swiss-Prot
    Q8BNU0, Q8C4P5, Q8C7S1, Q8K2S7, Q99JQ2, Q9CWE4
    Conserved Domains (2) summary
    smart00185
    Location:184 → 226
    ARM; Armadillo/beta-catenin-like repeats
    sd00043
    Location:146 → 180
    ARM; armadillo repeat [structural motif]

  4. XM_011242333.4 → XP_011240635.1  armadillo repeat-containing protein 6 isoform X1

    See identical proteins and their annotated locations for XP_011240635.1

    Conserved Domains (2) summary
    smart00185
    Location:184 → 226
    ARM; Armadillo/beta-catenin-like repeats
    sd00043
    Location:146 → 180
    ARM; armadillo repeat [structural motif]

  5. XM_011242334.3 → XP_011240636.1  armadillo repeat-containing protein 6 isoform X1

    See identical proteins and their annotated locations for XP_011240636.1

    Conserved Domains (2) summary
    smart00185
    Location:184 → 226
    ARM; Armadillo/beta-catenin-like repeats
    sd00043
    Location:146 → 180
    ARM; armadillo repeat [structural motif]
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BNU0.1 GenPept UniProtKB/Swiss-Prot:Q8BNU0

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