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Actrt3 actin related protein T3 [ Mus musculus (house mouse) ]

Gene ID: 76652, updated on 11-Apr-2024

Summary

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Official Symbol
Actrt3provided by MGI
Official Full Name
actin related protein T3provided by MGI
Primary source
MGI:MGI:1923902
See related
Ensembl:ENSMUSG00000037737 AllianceGenome:MGI:1923902
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Arpm1; ARP-T3; 1700119I24Rik
Summary
Located in male germ cell nucleus. Is expressed in several structures, including brain; genitourinary system; submandibular gland; and trachea. Orthologous to human ACTRT3 (actin related protein T3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 19.8) See more
Orthologs
human all
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Genomic context

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Location:
3 A3; 3 14.27 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (30651221..30654021, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (30597073..30599870, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene MDS1 and EVI1 complex locus Neighboring gene MDS1 and EVI1 complex locus, opposite strand Neighboring gene STARR-seq mESC enhancer starr_07290 Neighboring gene predicted gene 10258 Neighboring gene STARR-seq mESC enhancer starr_07292 Neighboring gene STARR-seq mESC enhancer starr_07293 Neighboring gene STARR-seq mESC enhancer starr_07294 Neighboring gene STARR-positive B cell enhancer ABC_E2661 Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:30500978-30501161 Neighboring gene nuclear encoded tRNA valine 8 (anticodon AAC) Neighboring gene myoneurin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Nuclear localization of profilin III-ArpM1 complex in mouse spermiogenesis. Hara Y, et al. FEBS Lett, 2008 Sep 3. PMID 18692047
  2. Molecular evolution of the actin family. Goodson HV, et al. J Cell Sci, 2002 Jul 1. PMID 12077353
  3. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (3) 

General gene information

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Markers

Homology

Clone Names

  • MGC130225

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
is_active_in actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in male germ cell nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
actin-related protein T3
Names
actin related protein M1
actin-related protein M1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029690.3 → NP_083966.1  actin-related protein T3

    See identical proteins and their annotated locations for NP_083966.1

    Status: VALIDATED

    Source sequence(s)
    AC119995
    Consensus CDS
    CCDS17283.1
    UniProtKB/Swiss-Prot
    Q3KNH6, Q8BXF8, Q9D9A6
    Related
    ENSMUSP00000048360.7, ENSMUST00000047630.7
    Conserved Domains (2) summary
    smart00268
    Location:5 → 369
    ACTIN; Actin
    cl17037
    Location:9 → 369
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    30651221..30654021 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BXF8.1 GenPept UniProtKB/Swiss-Prot:Q8BXF8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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