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Dnttip1 deoxynucleotidyltransferase, terminal, interacting protein 1 [ Mus musculus (house mouse) ]

Gene ID: 76233, updated on 21-Apr-2024

Summary

Official Symbol
Dnttip1provided by MGI
Official Full Name
deoxynucleotidyltransferase, terminal, interacting protein 1provided by MGI
Primary source
MGI:MGI:1923483
See related
Ensembl:ENSMUSG00000017299 AllianceGenome:MGI:1923483
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
6430706C13Rik
Summary
Predicted to enable several functions, including enzyme activator activity; nucleosome binding activity; and protein homodimerization activity. Predicted to be located in chromosome; nucleolus; and nucleoplasm. Predicted to be part of histone deacetylase complex. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and immune system. Orthologous to human DNTTIP1 (deoxynucleotidyltransferase terminal interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 32.6), CNS E14 (RPKM 24.1) and 28 other tissues See more
Orthologs
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Genomic context

Location:
2 H3; 2 85.27 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (164587935..164610140)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (164746015..164768220)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene serine protease inhibitor, Kunitz type 5 Neighboring gene WAP four-disulfide core domain 3 Neighboring gene STARR-seq mESC enhancer starr_06333 Neighboring gene STARR-positive B cell enhancer ABC_E417 Neighboring gene ubiquitin-conjugating enzyme E2C Neighboring gene troponin C2, fast

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (2) 
  • Endonuclease-mediated (1)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables DNA binding ISO
Inferred from Sequence Orthology
more info
PubMed 
enables enzyme activator activity ISO
Inferred from Sequence Orthology
more info
PubMed 
enables nucleosome binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables nucleosome binding ISO
Inferred from Sequence Orthology
more info
 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
PubMed 
Component Evidence Code Pubs
located_in chromosome ISO
Inferred from Sequence Orthology
more info
 
part_of histone deacetylase complex ISO
Inferred from Sequence Orthology
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
PubMed 

General protein information

Preferred Names
deoxynucleotidyltransferase terminal-interacting protein 1
Names
tdIF1
tdT-interacting factor 1
terminal deoxynucleotidyltransferase-interacting factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133763.1NP_598524.1  deoxynucleotidyltransferase terminal-interacting protein 1

    See identical proteins and their annotated locations for NP_598524.1

    Status: PROVISIONAL

    Source sequence(s)
    BC003486
    Consensus CDS
    CCDS17054.1
    UniProtKB/Swiss-Prot
    Q99LB0
    UniProtKB/TrEMBL
    Q3THA4
    Related
    ENSMUSP00000017443.8, ENSMUST00000017443.14

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    164587935..164610140
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)