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Fam184a family with sequence similarity 184, member A [ Mus musculus (house mouse) ]

Gene ID: 75906, updated on 5-Mar-2024

Summary

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Official Symbol
Fam184aprovided by MGI
Official Full Name
family with sequence similarity 184, member Aprovided by MGI
Primary source
MGI:MGI:1923156
See related
Ensembl:ENSMUSG00000019856 AllianceGenome:MGI:1923156
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
3110012E06Rik; 4930438C08Rik; 4930589M24Rik
Summary
Is expressed in medulla oblongata; midbrain; midbrain mantle layer; and pons. Orthologous to human FAM184A (family with sequence similarity 184 member A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in frontal lobe adult (RPKM 8.0), testis adult (RPKM 5.7) and 11 other tissues See more
Orthologs
human all
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Genomic context

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Location:
10 B3; 10 27.26 cM
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (53509131..53627368, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (53633035..53751277, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_26696 Neighboring gene STARR-seq mESC enhancer starr_26698 Neighboring gene predicted gene, 40650 Neighboring gene predicted gene, 20597 Neighboring gene STARR-seq mESC enhancer starr_26699 Neighboring gene STARR-positive B cell enhancer ABC_E6844 Neighboring gene minichromosome maintenance 9 homologous recombination repair factor Neighboring gene STARR-positive B cell enhancer ABC_E10606 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:53349966-53350075 Neighboring gene anti-silencing function 1A histone chaperone Neighboring gene mannosidase 1, alpha Neighboring gene STARR-positive B cell enhancer mm9_chr10:53704763-53705064 Neighboring gene STARR-positive B cell enhancer ABC_E6845 Neighboring gene STARR-positive B cell enhancer mm9_chr10:53735714-53736015 Neighboring gene predicted gene, 53584 Neighboring gene STARR-positive B cell enhancer mm9_chr10:53795485-53795786 Neighboring gene predicted gene, 16998

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Kim H, et al. Cell, 2018 Dec 13. PMID 30550785, Free PMC Article
  2. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in P-body ISO
Inferred from Sequence Orthology
more info
  
located_in centriolar satellite ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
protein FAM184A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081428.2 → NP_001074897.1  protein FAM184A

    Status: VALIDATED

    Source sequence(s)
    AC153949, AC164581
    Consensus CDS
    CCDS35901.1
    UniProtKB/TrEMBL
    E9PW83, F6TU77
    Related
    ENSMUSP00000020003.8, ENSMUST00000020003.15
    Conserved Domains (2) summary
    TIGR02168
    Location:228 → 1005
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15665
    Location:57 → 267
    FAM184; Family with sequence similarity 184, A and B

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    53509131..53627368 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036156072.1 → XP_036011965.1  protein FAM184A isoform X17

    UniProtKB/TrEMBL
    F6TU77
    Conserved Domains (2) summary
    COG1196
    Location:63 → 705
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam15665
    Location:57 → 267
    FAM184; Family with sequence similarity 184, A and B

  2. XM_017314135.3 → XP_017169624.1  protein FAM184A isoform X9

    UniProtKB/TrEMBL
    F6TU77
    Conserved Domains (2) summary
    TIGR02168
    Location:263 → 1019
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15665
    Location:57 → 267
    FAM184; Family with sequence similarity 184, A and B

  3. XM_006512897.5 → XP_006512960.1  protein FAM184A isoform X14

    UniProtKB/TrEMBL
    F6TU77
    Conserved Domains (2) summary
    TIGR02168
    Location:263 → 1019
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15665
    Location:57 → 267
    FAM184; Family with sequence similarity 184, A and B

  4. XM_030245348.2 → XP_030101208.1  protein FAM184A isoform X15

    UniProtKB/TrEMBL
    F6TU77
    Conserved Domains (2) summary
    TIGR02168
    Location:228 → 1005
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15665
    Location:57 → 267
    FAM184; Family with sequence similarity 184, A and B

  5. XM_006512893.5 → XP_006512956.1  protein FAM184A isoform X5

    UniProtKB/TrEMBL
    F6TU77
    Conserved Domains (2) summary
    COG1196
    Location:163 → 1002
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam15665
    Location:57 → 267
    FAM184; Family with sequence similarity 184, A and B

  6. XM_006512890.5 → XP_006512953.1  protein FAM184A isoform X2

    UniProtKB/TrEMBL
    F6TU77
    Conserved Domains (2) summary
    TIGR02168
    Location:263 → 1019
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15665
    Location:57 → 267
    FAM184; Family with sequence similarity 184, A and B

  7. XM_006512894.5 → XP_006512957.1  protein FAM184A isoform X6

    UniProtKB/TrEMBL
    F6TU77
    Conserved Domains (2) summary
    COG1196
    Location:163 → 988
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam15665
    Location:57 → 267
    FAM184; Family with sequence similarity 184, A and B

  8. XM_017314134.3 → XP_017169623.1  protein FAM184A isoform X7

    UniProtKB/TrEMBL
    F6TU77
    Conserved Domains (3) summary
    COG1196
    Location:46 → 705
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:737 → 992
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15665
    Location:57 → 267
    FAM184; Family with sequence similarity 184, A and B

  9. XM_006512889.5 → XP_006512952.1  protein FAM184A isoform X1

    UniProtKB/TrEMBL
    F6TU77
    Conserved Domains (2) summary
    TIGR02168
    Location:263 → 1019
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15665
    Location:57 → 267
    FAM184; Family with sequence similarity 184, A and B

  10. XM_011243225.4 → XP_011241527.1  protein FAM184A isoform X10

    UniProtKB/TrEMBL
    F6TU77
    Related
    ENSMUSP00000127400.2, ENSMUST00000163761.8
    Conserved Domains (3) summary
    COG1196
    Location:46 → 704
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:611 → 978
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15665
    Location:57 → 267
    FAM184; Family with sequence similarity 184, A and B

  11. XM_030245350.2 → XP_030101210.1  protein FAM184A isoform X21

    Conserved Domains (2) summary
    COG1196
    Location:47 → 313
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:127 → 515
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  12. XM_006512898.5 → XP_006512961.1  protein FAM184A isoform X18

    UniProtKB/TrEMBL
    F6RSY8
    Conserved Domains (2) summary
    TIGR02168
    Location:46 → 628
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    TIGR02169
    Location:127 → 331
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  13. XM_030245349.2 → XP_030101209.1  protein FAM184A isoform X19

    UniProtKB/TrEMBL
    F6RSY8
    Related
    ENSMUSP00000130315.2, ENSMUST00000171807.8
    Conserved Domains (1) summary
    COG1196
    Location:258 → 646
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  14. XM_006512891.5 → XP_006512954.1  protein FAM184A isoform X3

    UniProtKB/TrEMBL
    F6TU77
    Conserved Domains (2) summary
    TIGR02168
    Location:263 → 1019
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15665
    Location:57 → 267
    FAM184; Family with sequence similarity 184, A and B

  15. XM_017314133.3 → XP_017169622.1  protein FAM184A isoform X4

    UniProtKB/TrEMBL
    F6TU77
    Conserved Domains (2) summary
    TIGR02168
    Location:228 → 1005
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15665
    Location:57 → 267
    FAM184; Family with sequence similarity 184, A and B

  16. XM_036156073.1 → XP_036011966.1  protein FAM184A isoform X20

    UniProtKB/TrEMBL
    F6RSY8
    Conserved Domains (1) summary
    COG1196
    Location:47 → 313
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  17. XM_017314136.3 → XP_017169625.1  protein FAM184A isoform X12

    UniProtKB/TrEMBL
    F6TU77
    Conserved Domains (2) summary
    TIGR02168
    Location:228 → 1005
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15665
    Location:57 → 267
    FAM184; Family with sequence similarity 184, A and B

  18. XM_006512896.5 → XP_006512959.1  protein FAM184A isoform X13

    UniProtKB/TrEMBL
    F6TU77
    Conserved Domains (2) summary
    TIGR02168
    Location:263 → 1019
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15665
    Location:57 → 267
    FAM184; Family with sequence similarity 184, A and B

  19. XM_006512895.5 → XP_006512958.1  protein FAM184A isoform X8

    UniProtKB/TrEMBL
    F6TU77
    Conserved Domains (2) summary
    TIGR02168
    Location:263 → 1019
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15665
    Location:57 → 267
    FAM184; Family with sequence similarity 184, A and B

  20. XM_036156071.1 → XP_036011964.1  protein FAM184A isoform X16

    UniProtKB/TrEMBL
    F6TU77
    Conserved Domains (2) summary
    COG1196
    Location:163 → 988
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam15665
    Location:57 → 267
    FAM184; Family with sequence similarity 184, A and B

  21. XM_030245346.2 → XP_030101206.1  protein FAM184A isoform X11

    UniProtKB/TrEMBL
    F6TU77
    Conserved Domains (2) summary
    TIGR02168
    Location:228 → 1005
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15665
    Location:57 → 267
    FAM184; Family with sequence similarity 184, A and B

RNA

  1. XR_003948817.2 RNA Sequence

  2. XR_380088.5 RNA Sequence

  3. XR_004936297.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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