U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Fam227b family with sequence similarity 227, member B [ Mus musculus (house mouse) ]

Gene ID: 75823, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
Fam227bprovided by MGI
Official Full Name
family with sequence similarity 227, member Bprovided by MGI
Primary source
MGI:MGI:1923073
See related
Ensembl:ENSMUSG00000027209 AllianceGenome:MGI:1923073
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4930525F21Rik
Summary
Orthologous to human FAM227B (family with sequence similarity 227 member B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 11.1), large intestine adult (RPKM 2.9) and 11 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
2 F1; 2 61.76 cM
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (125825403..125994048, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (125983473..126152153, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene SECIS binding protein 2-like Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:125602741-125602942 Neighboring gene STARR-positive B cell enhancer ABC_E5976 Neighboring gene STARR-positive B cell enhancer ABC_E7857 Neighboring gene STARR-positive B cell enhancer ABC_E11156 Neighboring gene COP9 signalosome subunit 2 Neighboring gene galactokinase 2 Neighboring gene fibroblast growth factor 7 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:125977713-125977822 Neighboring gene predicted gene, 26496 Neighboring gene DTW domain containing 1 Neighboring gene STARR-seq mESC enhancer starr_05598 Neighboring gene predicted gene, 54149 Neighboring gene STARR-seq mESC enhancer starr_05599 Neighboring gene STARR-seq mESC enhancer starr_05600 Neighboring gene STARR-positive B cell enhancer ABC_E2643 Neighboring gene STARR-seq mESC enhancer starr_05601 Neighboring gene STARR-seq mESC enhancer starr_05602 Neighboring gene STARR-seq mESC enhancer starr_05603 Neighboring gene STARR-positive B cell enhancer mm9_chr2:126188755-126189056 Neighboring gene ATPase, class I, type 8B, member 4 Neighboring gene Brca1 associated protein 1 pseudogene

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  2. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

Go to the top of the page Help
Preferred Names
protein FAM227B

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029455.3 → NP_083731.2  protein FAM227B

    See identical proteins and their annotated locations for NP_083731.2

    Status: VALIDATED

    Source sequence(s)
    AL845292, AL929175
    Consensus CDS
    CCDS50697.1
    UniProtKB/Swiss-Prot
    A2AR82, Q9D518
    Related
    ENSMUSP00000106076.3, ENSMUST00000110446.9
    Conserved Domains (1) summary
    pfam14922
    Location:143 → 293
    FWWh; Protein of unknown function

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    125825403..125994048 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006500348.5 → XP_006500411.1  protein FAM227B isoform X1

    Conserved Domains (1) summary
    pfam14922
    Location:213 → 358
    FWWh; Protein of unknown function

  2. XM_006500349.3 → XP_006500412.1  protein FAM227B isoform X2

    Conserved Domains (1) summary
    pfam14922
    Location:51 → 196
    FWWh; Protein of unknown function

  3. XM_006500350.3 → XP_006500413.1  protein FAM227B isoform X3

    Conserved Domains (1) summary
    pfam14922
    Location:19 → 164
    FWWh; Protein of unknown function
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D518.3 GenPept UniProtKB/Swiss-Prot:Q9D518

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous