U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Fam227a family with sequence similarity 227, member A [ Mus musculus (house mouse) ]

Gene ID: 75729, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
Fam227aprovided by MGI
Official Full Name
family with sequence similarity 227, member Aprovided by MGI
Primary source
MGI:MGI:1922979
See related
Ensembl:ENSMUSG00000042564 AllianceGenome:MGI:1922979
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4933432B09Rik
Summary
Orthologous to human FAM227A (family with sequence similarity 227 member A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in whole brain E14.5 (RPKM 3.4), testis adult (RPKM 3.1) and 13 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
15 E1; 15 37.81 cM
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (79493777..79543157, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (79609576..79658956, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 Neighboring gene DEAD box helicase 17 Neighboring gene STARR-seq mESC enhancer starr_39189 Neighboring gene DNA meiotic recombinase 1 Neighboring gene STARR-seq mESC enhancer starr_39191 Neighboring gene STARR-seq mESC enhancer starr_39193 Neighboring gene predicted gene, 30877 Neighboring gene chibby family member 1, beta catenin antagonist Neighboring gene translocase of outer mitochondrial membrane 22

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

Go to the top of the page Help
Preferred Names
protein FAM227A

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029407.1 → NP_083683.1  protein FAM227A

    See identical proteins and their annotated locations for NP_083683.1

    Status: VALIDATED

    Source sequence(s)
    AC117806, AK017017, AK039547
    Consensus CDS
    CCDS79389.1
    UniProtKB/TrEMBL
    Q9D3V8
    Related
    ENSMUSP00000139524.2, ENSMUST00000187519.7
    Conserved Domains (1) summary
    pfam14922
    Location:145 → 295
    FWWh; Protein of unknown function

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    79493777..79543157 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030248810.1 → XP_030104670.1  protein FAM227A isoform X6

    Conserved Domains (1) summary
    pfam14922
    Location:15 → 138
    FWWh; Protein of unknown function

  2. XM_030248811.1 → XP_030104671.1  protein FAM227A isoform X7

    Conserved Domains (1) summary
    pfam14922
    Location:1 → 104
    FWWh; Protein of unknown function

  3. XM_030248809.1 → XP_030104669.1  protein FAM227A isoform X2

    UniProtKB/TrEMBL
    A0A2R8VHN9
    Related
    ENSMUSP00000155261.2, ENSMUST00000229064.2
    Conserved Domains (1) summary
    pfam14922
    Location:141 → 291
    FWWh; Protein of unknown function

  4. XM_030248813.2 → XP_030104673.1  protein FAM227A isoform X10

  5. XM_006521510.4 → XP_006521573.1  protein FAM227A isoform X5

    See identical proteins and their annotated locations for XP_006521573.1

    Conserved Domains (1) summary
    pfam14922
    Location:76 → 226
    FWWh; Protein of unknown function

  6. XM_017316779.2 → XP_017172268.1  protein FAM227A isoform X4

    Conserved Domains (1) summary
    pfam14922
    Location:141 → 239
    FWWh; Protein of unknown function

  7. XM_017316777.2 → XP_017172266.1  protein FAM227A isoform X2

    UniProtKB/TrEMBL
    A0A2R8VHN9
    Conserved Domains (1) summary
    pfam14922
    Location:141 → 291
    FWWh; Protein of unknown function

  8. XM_017316778.2 → XP_017172267.1  protein FAM227A isoform X3

    Conserved Domains (1) summary
    pfam14922
    Location:145 → 243
    FWWh; Protein of unknown function

  9. XM_011245765.3 → XP_011244067.1  protein FAM227A isoform X1

    See identical proteins and their annotated locations for XP_011244067.1

    UniProtKB/TrEMBL
    Q9D3V8
    Conserved Domains (1) summary
    pfam14922
    Location:145 → 295
    FWWh; Protein of unknown function

  10. XM_011245760.3 → XP_011244062.1  protein FAM227A isoform X5

    See identical proteins and their annotated locations for XP_011244062.1

    Conserved Domains (1) summary
    pfam14922
    Location:76 → 226
    FWWh; Protein of unknown function

  11. XM_017316781.3 → XP_017172270.1  protein FAM227A isoform X6

    Conserved Domains (1) summary
    pfam14922
    Location:15 → 138
    FWWh; Protein of unknown function

  12. XM_011245764.2 → XP_011244066.1  protein FAM227A isoform X12

    UniProtKB/TrEMBL
    Q08EB1

  13. XM_017316784.2 → XP_017172273.1  protein FAM227A isoform X9

    Conserved Domains (1) summary
    pfam14922
    Location:145 → 295
    FWWh; Protein of unknown function

  14. XM_017316783.2 → XP_017172272.1  protein FAM227A isoform X8

    Conserved Domains (1) summary
    pfam14922
    Location:145 → 295
    FWWh; Protein of unknown function

  15. XM_017316785.2 → XP_017172274.1  protein FAM227A isoform X11

    Conserved Domains (1) summary
    pfam14922
    Location:145 → 295
    FWWh; Protein of unknown function

  16. XM_036159622.1 → XP_036015515.1  protein FAM227A isoform X11

    Conserved Domains (1) summary
    pfam14922
    Location:145 → 295
    FWWh; Protein of unknown function

RNA

  1. XR_004938876.1 RNA Sequence

  2. XR_003951444.1 RNA Sequence

  3. XR_001781574.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous