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Rasl10a RAS-like, family 10, member A [ Mus musculus (house mouse) ]

Gene ID: 75668, updated on 5-Mar-2024

Summary

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Official Symbol
Rasl10aprovided by MGI
Official Full Name
RAS-like, family 10, member Aprovided by MGI
Primary source
MGI:MGI:1922918
See related
Ensembl:ENSMUSG00000034209 AllianceGenome:MGI:1922918
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2210403B10Rik
Summary
Predicted to enable G protein activity and GTP binding activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus and plasma membrane. Orthologous to human RASL10A (RAS like family 10 member A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in ovary adult (RPKM 36.8), cortex adult (RPKM 19.9) and 8 other tissues See more
Orthologs
human all
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Genomic context

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Location:
11 A1; 11 3.21 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (5008128..5010385)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (5058128..5060385)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 35321 Neighboring gene STARR-seq mESC enhancer starr_28417 Neighboring gene neurofilament, heavy polypeptide Neighboring gene adaptor protein complex AP-1, beta 1 subunit Neighboring gene STARR-positive B cell enhancer ABC_E5205 Neighboring gene predicted gene, 24958 Neighboring gene growth arrest-specific 2 like 1 Neighboring gene Ewing sarcoma breakpoint region 1 Neighboring gene STARR-positive B cell enhancer ABC_E8383 Neighboring gene STARR-positive B cell enhancer ABC_E11468 Neighboring gene rhomboid domain containing 3 Neighboring gene EMI domain containing 1 Neighboring gene predicted gene, 46266

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. High-throughput sequence identification of gene coding variants within alcohol-related QTLs. Ehringer MA, et al. Mamm Genome, 2001 Aug. PMID 11471062
  2. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
  3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC130093, MGC130094

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein activity IEA
Inferred from Electronic Annotation
more info
  
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ras-like protein family member 10A
Names
Ras-like protein RRP22 (RAS-related protein on chromosome 22)
ras-related protein on chromosome 22 homolog
NP_001350108.1
NP_660251.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001363179.1 → NP_001350108.1  ras-like protein family member 10A isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL645522
    Conserved Domains (1) summary
    cl21455
    Location:5 → 113
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  2. NM_145216.4 → NP_660251.1  ras-like protein family member 10A isoform 1

    See identical proteins and their annotated locations for NP_660251.1

    Status: VALIDATED

    Source sequence(s)
    AK044011, AL645522, AV078172
    Consensus CDS
    CCDS24394.1
    UniProtKB/Swiss-Prot
    Q3KNN0, Q8K5A4
    Related
    ENSMUSP00000048453.2, ENSMUST00000037218.2
    Conserved Domains (2) summary
    smart00173
    Location:6 → 176
    RAS; Ras subfamily of RAS small GTPases
    cl21455
    Location:5 → 203
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    5008128..5010385
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8K5A4.1 GenPept UniProtKB/Swiss-Prot:Q8K5A4

Gene LinkOut

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