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Dynap dynactin associated protein [ Mus musculus (house mouse) ]

Gene ID: 75577, updated on 8-Feb-2024

Summary

Official Symbol
Dynapprovided by MGI
Official Full Name
dynactin associated proteinprovided by MGI
Primary source
MGI:MGI:1922827
See related
Ensembl:ENSMUSG00000024512 AllianceGenome:MGI:1922827
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2310002L13Rik
Summary
Predicted to be involved in several processes, including activation of protein kinase B activity; cellular response to ergosterol; and positive regulation of cell population proliferation. Predicted to be active in Golgi apparatus and plasma membrane. Orthologous to human DYNAP (dynactin associated protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

Location:
18 E2; 18 44.21 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (70373500..70377655, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (70240429..70244584, complement)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_44955 Neighboring gene coiled-coil domain containing 68 Neighboring gene crumbs homolog 1 pseudogene Neighboring gene RAB27B, member RAS oncogene family Neighboring gene STARR-seq mESC enhancer starr_44957 Neighboring gene predicted gene, 41770 Neighboring gene STARR-seq mESC enhancer starr_44958 Neighboring gene STARR-seq mESC enhancer starr_44960 Neighboring gene dynactin associated protein like 1 Neighboring gene STARR-seq mESC enhancer starr_44961 Neighboring gene STARR-seq mESC enhancer starr_44962 Neighboring gene predicted gene, 31620

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in activation of protein kinase B activity IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in activation of protein kinase B activity ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to ergosterol ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cell population proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
dynactin-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029346.1NP_083622.1  dynactin-associated protein

    See identical proteins and their annotated locations for NP_083622.1

    Status: VALIDATED

    Source sequence(s)
    AC124764, AK009098
    Consensus CDS
    CCDS50316.1
    UniProtKB/TrEMBL
    G8CXX7, Q9D7M5
    Related
    ENSMUSP00000025390.3, ENSMUST00000025390.4
    Conserved Domains (1) summary
    pfam15675
    Location:5179
    CLLAC; CLLAC-motif containing domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    70373500..70377655 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)