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Capsl calcyphosine-like [ Mus musculus (house mouse) ]

Gene ID: 75568, updated on 18-Apr-2024

Summary

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Official Symbol
Capslprovided by MGI
Official Full Name
calcyphosine-likeprovided by MGI
Primary source
MGI:MGI:1922818
See related
Ensembl:ENSMUSG00000039676 AllianceGenome:MGI:1922818
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700028N11Rik
Summary
Predicted to enable calcium ion binding activity. Predicted to be located in cytoplasm. Is expressed in several structures, including brain ventricle and choroid plexus; extraembryonic ectoderm; nasal cavity epithelium; pancreas epithelium; and primitive streak. Orthologous to human CAPSL (calcyphosine like). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis adult (RPKM 3.0), bladder adult (RPKM 2.2) and 18 other tissues See more
Orthologs
human all
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Genomic context

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Location:
15 A1; 15 4.09 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (9436136..9466125)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (9436016..9466039)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_37936 Neighboring gene UDP glycosyltransferases 3 family, polypeptide A2 Neighboring gene STARR-seq mESC enhancer starr_37937 Neighboring gene STARR-seq mESC enhancer starr_37938 Neighboring gene STARR-seq mESC enhancer starr_37939 Neighboring gene UDP glycosyltransferases 3 family, polypeptide A1 pseudogene Neighboring gene interleukin 7 receptor Neighboring gene sperm flagellar 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Efficient gene-driven germ-line point mutagenesis of C57BL/6J mice. Michaud EJ, et al. BMC Genomics, 2005 Nov 21. PMID 16300676, Free PMC Article
  2. Characterizing embryonic gene expression patterns in the mouse using nonredundant sequence-based selection. Sousa-Nunes R, et al. Genome Res, 2003 Dec. PMID 14613977, Free PMC Article
  3. A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b Signaling on Epithelial Tip Progenitor Cells During Early Mouse Lung Branching Morphogenesis. Jones MR, et al. Front Genet, 2018. PMID 30728831, Free PMC Article
  4. Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo. Harrison SM, et al. Development, 1995 Aug. PMID 7671812
  5. Identification of transcripts with enriched expression in the developing and adult pancreas. Hoffman BG, et al. Genome Biol, 2008. PMID 18554416, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Chemically induced (ENU) (2)  1 citation
  • Targeted (1) 

General gene information

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Markers

Homology

Clone Names

  • MGC74120

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
calcyphosin-like protein
Names
Calcyphosine

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001418759.1 → NP_001405688.1  calcyphosin-like protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC162301
    UniProtKB/TrEMBL
    A0A2I3BPX5
    Related
    ENSMUSP00000153958.2, ENSMUST00000226688.2

  2. NM_029341.2 → NP_083617.2  calcyphosin-like protein isoform 1

    See identical proteins and their annotated locations for NP_083617.2

    Status: VALIDATED

    Source sequence(s)
    AC162301
    Consensus CDS
    CCDS37040.1
    UniProtKB/Swiss-Prot
    Q5U5X2, Q6P8Y1, Q9D9U6
    Related
    ENSMUSP00000035663.4, ENSMUST00000042360.5
    Conserved Domains (3) summary
    cd00051
    Location:46 → 101
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam13499
    Location:80 → 140
    EF-hand_7; EF-hand domain pair
    cl08302
    Location:116 → 182
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    9436136..9466125
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006520185.2 → XP_006520248.1  calcyphosin-like protein isoform X1

    Conserved Domains (1) summary
    pfam13499
    Location:65 → 137
    EF-hand_7; EF-hand domain pair
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6P8Y1.4 GenPept UniProtKB/Swiss-Prot:Q6P8Y1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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