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Bcdin3d BCDIN3 domain containing [ Mus musculus (house mouse) ]

Gene ID: 75284, updated on 11-Apr-2024

Summary

Official Symbol
Bcdin3dprovided by MGI
Official Full Name
BCDIN3 domain containingprovided by MGI
Primary source
MGI:MGI:1922534
See related
Ensembl:ENSMUSG00000037525 AllianceGenome:MGI:1922534
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4930556P03Rik
Summary
Predicted to enable O-methyltransferase activity and tRNA methyltransferase activity. Predicted to be involved in miRNA 2'-O-methylation; negative regulation of pre-miRNA processing; and tRNA methylation. Predicted to act upstream of or within methylation. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cytoplasm. Orthologous to human BCDIN3D (BCDIN3 domain containing RNA methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 5.3), CNS E14 (RPKM 5.3) and 28 other tissues See more
Orthologs
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Genomic context

Location:
15 F1; 15 56.13 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (99367965..99372611, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (99470084..99474730, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene transmembrane BAX inhibitor motif containing 6 Neighboring gene STARR-positive B cell enhancer ABC_E761 Neighboring gene VISTA enhancer mm1635 Neighboring gene NCK-associated protein 5-like Neighboring gene NCK-associated protein 5-like, opposite strand Neighboring gene STARR-positive B cell enhancer ABC_E5516 Neighboring gene Fas apoptotic inhibitory molecule 2 Neighboring gene predicted gene 5808

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables O-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables O-methyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables RNA methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA methyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables pre-miRNA binding ISO
Inferred from Sequence Orthology
more info
 
enables small RNA 2'-O-methyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables tRNA methyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in RNA methylation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within methylation IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of pre-miRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in negative regulation of pre-miRNA processing ISO
Inferred from Sequence Orthology
more info
 
involved_in pre-miRNA processing ISO
Inferred from Sequence Orthology
more info
 
involved_in tRNA methylation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
RNA 5'-monophosphate methyltransferase
Names
BCDIN3 domain-containing protein
pre-miRNA 5'-monophosphate methyltransferase
probable methyltransferase BCDIN3D
NP_083512.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029236.2NP_083512.2  RNA 5'-monophosphate methyltransferase

    See identical proteins and their annotated locations for NP_083512.2

    Status: VALIDATED

    Source sequence(s)
    BQ557755, BY262678, CO427236
    Consensus CDS
    CCDS37202.1
    UniProtKB/Swiss-Prot
    Q91YP1, Q9D4U5
    Related
    ENSMUSP00000041809.5, ENSMUST00000040313.6
    Conserved Domains (2) summary
    pfam06859
    Location:159264
    Bin3; Bicoid-interacting protein 3 (Bin3)
    pfam12847
    Location:72190
    Methyltransf_18; Methyltransferase domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    99367965..99372611 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)