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Prr3 proline-rich polypeptide 3 [ Mus musculus (house mouse) ]

Gene ID: 75210, updated on 5-Mar-2024

Summary

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Official Symbol
Prr3provided by MGI
Official Full Name
proline-rich polypeptide 3provided by MGI
Primary source
MGI:MGI:1922460
See related
Ensembl:ENSMUSG00000038500 AllianceGenome:MGI:1922460
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Cat56; 4930540G07Rik
Summary
Predicted to enable metal ion binding activity. Is expressed in early conceptus; inner cell mass; and oocyte. Orthologous to human PRR3 (proline rich 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E18 (RPKM 13.4), whole brain E14.5 (RPKM 13.0) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Prr3 in Genome Data Viewer
Location:
17 B1; 17 18.81 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (36283431..36291136, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (35972539..35980244, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene protein phosphatase 1, regulatory subunit 10 pseudogene Neighboring gene ATP-binding cassette, sub-family F member 1 Neighboring gene microRNA 877 Neighboring gene STARR-positive B cell enhancer ABC_E8674 Neighboring gene predicted gene, 32655 Neighboring gene guanine nucleotide binding protein-like 1 Neighboring gene RIKEN cDNA A930015D03 gene Neighboring gene STARR-positive B cell enhancer ABC_E5609 Neighboring gene STARR-positive B cell enhancer ABC_E8921 Neighboring gene STARR-positive B cell enhancer ABC_E959 Neighboring gene STARR-positive B cell enhancer ABC_E4214 Neighboring gene STARR-positive B cell enhancer ABC_E5610 Neighboring gene STARR-positive B cell enhancer ABC_E9951 Neighboring gene histocompatibility 2, T region locus 24 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:36157683-36157870 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:36160698-36160881 Neighboring gene STARR-positive B cell enhancer ABC_E8675 Neighboring gene histocompatibility 2, T region locus 23

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia. Carninci P, et al. Genome Res, 2003 Jun. PMID 12819125, Free PMC Article
  2. Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray. Nishimura M, et al. DNA Res, 2004 Oct 31. PMID 15747579
  3. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
  4. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  5. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
proline-rich protein 3
Names
MHC class I region proline-rich protein Cat56

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001165892.2 → NP_001159364.1  proline-rich protein 3 isoform b

    See identical proteins and their annotated locations for NP_001159364.1

    Status: VALIDATED

    Source sequence(s)
    AC112970
    Consensus CDS
    CCDS50099.1
    UniProtKB/TrEMBL
    E9Q601, G3UZI1
    Related
    ENSMUSP00000125802.3, ENSMUST00000165613.9

  2. NM_001282012.2 → NP_001268941.1  proline-rich protein 3 isoform c

    See identical proteins and their annotated locations for NP_001268941.1

    Status: VALIDATED

    Source sequence(s)
    AC112970
    Consensus CDS
    CCDS70807.1
    UniProtKB/TrEMBL
    Q3V0R7, Q4W8V0
    Related
    ENSMUSP00000129651.2, ENSMUST00000172429.8
    Conserved Domains (1) summary
    pfam00642
    Location:112 → 136
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

  3. NM_001282013.2 → NP_001268942.1  proline-rich protein 3 isoform c

    See identical proteins and their annotated locations for NP_001268942.1

    Status: VALIDATED

    Source sequence(s)
    AC112970
    Consensus CDS
    CCDS70807.1
    UniProtKB/TrEMBL
    Q3V0R7, Q4W8V0
    Conserved Domains (1) summary
    pfam00642
    Location:112 → 136
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

  4. NM_001282024.2 → NP_001268953.1  proline-rich protein 3 isoform c

    See identical proteins and their annotated locations for NP_001268953.1

    Status: VALIDATED

    Source sequence(s)
    AC112970
    Consensus CDS
    CCDS70807.1
    UniProtKB/TrEMBL
    Q3V0R7, Q4W8V0
    Conserved Domains (1) summary
    pfam00642
    Location:112 → 136
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

  5. NM_001282025.2 → NP_001268954.2  proline-rich protein 3 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC112970
    UniProtKB/TrEMBL
    E9Q601, G3UZI1
    Related
    ENSMUSP00000134115.2, ENSMUST00000172900.8

  6. NM_001384114.1 → NP_001371043.1  proline-rich protein 3 isoform a

    Status: VALIDATED

    Source sequence(s)
    AC112970
    UniProtKB/Swiss-Prot
    Q811B5, Q91YI5
    Conserved Domains (1) summary
    pfam00642
    Location:159 → 183
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

  7. NM_001384116.1 → NP_001371045.1  proline-rich protein 3 isoform e

    Status: VALIDATED

    Source sequence(s)
    AC112970
    Conserved Domains (1) summary
    pfam00642
    Location:62 → 86
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

  8. NM_001384117.1 → NP_001371046.1  proline-rich protein 3 isoform f

    Status: VALIDATED

    Source sequence(s)
    AC112970
    Conserved Domains (1) summary
    pfam00642
    Location:55 → 79
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

  9. NM_145487.4 → NP_663462.2  proline-rich protein 3 isoform a

    See identical proteins and their annotated locations for NP_663462.2

    Status: VALIDATED

    Source sequence(s)
    AC112970
    Consensus CDS
    CCDS28714.1
    UniProtKB/Swiss-Prot
    Q811B5, Q91YI5
    Related
    ENSMUSP00000052166.8, ENSMUST00000055454.14
    Conserved Domains (1) summary
    pfam00642
    Location:159 → 183
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    36283431..36291136 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030250122.2 → XP_030105982.1  proline-rich protein 3 isoform X1

  2. XM_036160820.1 → XP_036016713.1  proline-rich protein 3 isoform X2

RNA

  1. XR_001782124.3 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q811B5.1 GenPept UniProtKB/Swiss-Prot:Q811B5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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