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Tmbim7 transmembrane BAX inhibitor motif containing 7 [ Mus musculus (house mouse) ]

Gene ID: 75010, updated on 5-Mar-2024

Summary

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Official Symbol
Tmbim7provided by MGI
Official Full Name
transmembrane BAX inhibitor motif containing 7provided by MGI
Primary source
MGI:MGI:1922305
See related
Ensembl:ENSMUSG00000014529 AllianceGenome:MGI:1922305
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Lfg5; Lgf5; Tmbim1b; 4930403J02Rik; 4930500J03Rik; 4930511M11Rik
Summary
Is expressed in ductus deferens; epididymis; ileum; prostate gland; and testis. Orthologous to human TMBIM7P (transmembrane BAX inhibitor motif containing 7, pseudogene). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 33.5) See more
Orthologs
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Genomic context

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See Tmbim7 in Genome Data Viewer
Location:
5 A1; 5 2.26 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (3707004..3729865)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (3657004..3679865)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E429 Neighboring gene RNA binding motif protein 48 Neighboring gene peroxisomal biogenesis factor 1 Neighboring gene STARR-seq mESC enhancer starr_12316 Neighboring gene GATA zinc finger domain containing 1 Neighboring gene predicted gene, 50624 Neighboring gene STARR-seq mESC enhancer starr_12317 Neighboring gene ankyrin repeat and IBR domain containing 1 Neighboring gene STARR-positive B cell enhancer ABC_E4742 Neighboring gene STARR-seq mESC enhancer starr_12318 Neighboring gene KRIT1, ankyrin repeat containing

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
  2. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
bax inhibitor 1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029141.4 → NP_083417.1  bax inhibitor 1-like isoform b

    See identical proteins and their annotated locations for NP_083417.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. It encodes isoform b which is shorter than isoform a.
    Source sequence(s)
    AC022236, AC090443
    Consensus CDS
    CCDS19067.1
    UniProtKB/TrEMBL
    Q9D592
    Related
    ENSMUSP00000014673.3, ENSMUST00000014673.9
    Conserved Domains (1) summary
    cd10428
    Location:84 → 301
    LFG_like; Proteins similar to and including lifeguard (LFG), a putative regulator of apoptosis

  2. NM_029154.1 → NP_083430.1  bax inhibitor 1-like isoform a

    See identical proteins and their annotated locations for NP_083430.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AC022236, AC090443, AK015761
    Consensus CDS
    CCDS80202.1
    UniProtKB/TrEMBL
    Q9D561
    Related
    ENSMUSP00000143399.2, ENSMUST00000198739.5
    Conserved Domains (1) summary
    cd10428
    Location:28 → 223
    LFG_like; Proteins similar to and including lifeguard (LFG), a putative regulator of apoptosis

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    3707004..3729865
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006503611.4 → XP_006503674.1  bax inhibitor 1-like isoform X1

    Conserved Domains (1) summary
    cd10428
    Location:84 → 287
    LFG_like; Proteins similar to and including lifeguard (LFG), a putative regulator of apoptosis

  2. XM_006503614.4 → XP_006503677.1  bax inhibitor 1-like isoform X4

    Conserved Domains (1) summary
    cl00473
    Location:84 → 137
    BI-1-like; BAX inhibitor (BI)-1/YccA-like protein family

  3. XM_017321125.2 → XP_017176614.1  bax inhibitor 1-like isoform X3

    UniProtKB/TrEMBL
    F7AB47
    Related
    ENSMUSP00000117435.2, ENSMUST00000156117.2
    Conserved Domains (1) summary
    cl00473
    Location:84 → 241
    BI-1-like; BAX inhibitor (BI)-1/YccA-like protein family

  4. XM_006503612.4 → XP_006503675.1  bax inhibitor 1-like isoform X2

    UniProtKB/TrEMBL
    F7AB47
    Conserved Domains (1) summary
    cl00473
    Location:84 → 255
    BI-1-like; BAX inhibitor (BI)-1/YccA-like protein family

  5. XM_030254863.1 → XP_030110723.1  bax inhibitor 1-like isoform X5

    Conserved Domains (1) summary
    cl00473
    Location:1 → 160
    BI-1-like; BAX inhibitor (BI)-1/YccA-like protein family
Nucleotide Protein Strain
Heading Accession and Version

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