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Yipf2 Yip1 domain family, member 2 [ Mus musculus (house mouse) ]

Gene ID: 74766, updated on 11-Apr-2024

Summary

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Official Symbol
Yipf2provided by MGI
Official Full Name
Yip1 domain family, member 2provided by MGI
Primary source
MGI:MGI:1922016
See related
Ensembl:ENSMUSG00000032182 AllianceGenome:MGI:1922016
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1300010K09Rik
Summary
Predicted to enable small GTPase binding activity. Predicted to be involved in vesicle-mediated transport. Predicted to be located in Golgi apparatus subcompartment and transport vesicle. Predicted to be active in Golgi apparatus. Orthologous to human YIPF2 (Yip1 domain family member 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 51.9), genital fat pad adult (RPKM 45.7) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Yipf2 in Genome Data Viewer
Location:
9 A3; 9 7.83 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (21499978..21504131, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (21588682..21592831, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene cDNA sequence AB124611 Neighboring gene STARR-positive B cell enhancer ABC_E11402 Neighboring gene STARR-positive B cell enhancer mm9_chr9:21350851-21351152 Neighboring gene coactivator-associated arginine methyltransferase 1 Neighboring gene predicted gene, 39303 Neighboring gene STARR-seq mESC enhancer starr_23505 Neighboring gene translocase of inner mitochondrial membrane 29 Neighboring gene predicted gene 7904 Neighboring gene microRNA 1946b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Endonuclease-mediated (1) 

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi medial cisterna ISO
Inferred from Sequence Orthology
more info
  
located_in Golgi trans cisterna ISO
Inferred from Sequence Orthology
more info
  
located_in endosome IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in trans-Golgi network ISO
Inferred from Sequence Orthology
more info
  
located_in transport vesicle ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
protein YIPF2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001205157.1 → NP_001192086.1  protein YIPF2

    See identical proteins and their annotated locations for NP_001192086.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1, 2, 3, 5 and 6 encode the same protein.
    Source sequence(s)
    AC163748, AK133631, CD774249
    Consensus CDS
    CCDS22907.1
    UniProtKB/Swiss-Prot
    Q99LF3, Q99LP8
    Related
    ENSMUSP00000136463.2, ENSMUST00000180365.9
    Conserved Domains (1) summary
    pfam04893
    Location:84 → 245
    Yip1; Yip1 domain

  2. NM_001205158.1 → NP_001192087.1  protein YIPF2

    See identical proteins and their annotated locations for NP_001192087.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in both the 5' UTR and 3' UTR, compared to variant 1. Variants 1, 2, 3, 5 and 6 encode the same protein.
    Source sequence(s)
    AC163748
    Consensus CDS
    CCDS22907.1
    UniProtKB/Swiss-Prot
    Q99LF3, Q99LP8
    Related
    ENSMUSP00000077649.8, ENSMUST00000078572.9
    Conserved Domains (1) summary
    pfam04893
    Location:84 → 245
    Yip1; Yip1 domain

  3. NM_001359298.1 → NP_001346227.1  protein YIPF2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 3' UTR, compared to variant 1. Variants 1, 2, 3, 5 and 6 encode the same protein.
    Source sequence(s)
    AC163748
    Consensus CDS
    CCDS22907.1
    UniProtKB/Swiss-Prot
    Q99LF3, Q99LP8
    Conserved Domains (1) summary
    pfam04893
    Location:84 → 245
    Yip1; Yip1 domain

  4. NM_001359299.1 → NP_001346228.1  protein YIPF2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in both the 5' UTR and 3' UTR, compared to variant 1. Variants 1, 2, 3, 5 and 6 encode the same protein.
    Source sequence(s)
    AC163748
    Consensus CDS
    CCDS22907.1
    UniProtKB/Swiss-Prot
    Q99LF3, Q99LP8
    Conserved Domains (1) summary
    pfam04893
    Location:84 → 245
    Yip1; Yip1 domain

  5. NM_138303.2 → NP_612176.1  protein YIPF2

    See identical proteins and their annotated locations for NP_612176.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, 3, 5 and 6 encode the same protein.
    Source sequence(s)
    AC163748
    Consensus CDS
    CCDS22907.1
    UniProtKB/Swiss-Prot
    Q99LF3, Q99LP8
    Related
    ENSMUSP00000034700.8, ENSMUST00000034700.15
    Conserved Domains (1) summary
    pfam04893
    Location:84 → 245
    Yip1; Yip1 domain

RNA

  1. NR_038062.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in both the 5' and 3' terminal exons, compared to variant 1. This variant is represented as non-coding because it lacks the translational start codon found in variant 1, and it does not contain any alternate open reading frames that are likely to result in a protein.
    Source sequence(s)
    AA967152, AK004959, CD774249
    Related
    ENSMUST00000213809.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    21499978..21504131 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011242618.4 → XP_011240920.1  protein YIPF2 isoform X1

    See identical proteins and their annotated locations for XP_011240920.1

    UniProtKB/Swiss-Prot
    Q99LF3, Q99LP8
    Conserved Domains (1) summary
    pfam04893
    Location:84 → 245
    Yip1; Yip1 domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q99LP8.1 GenPept UniProtKB/Swiss-Prot:Q99LP8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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