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Rnf138rt1 ring finger protein 138, retrogene 1 [ Mus musculus (house mouse) ]

Gene ID: 74264, updated on 5-Mar-2024

Summary

Official Symbol
Rnf138rt1provided by MGI
Official Full Name
ring finger protein 138, retrogene 1provided by MGI
Primary source
MGI:MGI:1921514
See related
Ensembl:ENSMUSG00000083695 AllianceGenome:MGI:1921514
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable protein kinase binding activity; single-stranded DNA binding activity; and ubiquitin protein ligase activity. Predicted to be involved in DNA double-strand break processing involved in repair via single-strand annealing; double-strand break repair via homologous recombination; and protein ubiquitination. Predicted to be active in site of double-strand break. Orthologous to human RNF138 (ring finger protein 138). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
X F5; X 75.84 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (162543135..162544328, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (163760139..163761332, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene fusion, derived from t(12;16) malignant liposarcoma pseudogene Neighboring gene gastrin releasing peptide receptor Neighboring gene STARR-seq mESC enhancer starr_48232 Neighboring gene STARR-seq mESC enhancer starr_48234 Neighboring gene uncharacterized protein C8orf59 homolog Neighboring gene STARR-positive B cell enhancer ABC_E11688 Neighboring gene predicted gene, 52456 Neighboring gene adaptor-related protein complex 1, sigma 2 subunit

Genomic regions, transcripts, and products

General gene information

Markers

Clone Names

  • 1700045I19Rik

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables single-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables single-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ubiquitin protein ligase activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in site of double-strand break IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in site of double-strand break ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
E3 ubiquitin-protein ligase RNF138-like
Names
ring finger protein 138 pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028842.3NP_083118.1  E3 ubiquitin-protein ligase RNF138-like

    See identical proteins and their annotated locations for NP_083118.1

    Status: VALIDATED

    Source sequence(s)
    AI853461, AK006700, BY238719
    Consensus CDS
    CCDS72464.1
    UniProtKB/TrEMBL
    Q9D9M9
    Related
    ENSMUSP00000139291.2, ENSMUST00000059320.4
    Conserved Domains (2) summary
    cd00162
    Location:1962
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    pfam05605
    Location:159218
    zf-Di19; Drought induced 19 protein (Di19), zinc-binding

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    162543135..162544328 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)