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Tm9sf1 transmembrane 9 superfamily member 1 [ Mus musculus (house mouse) ]

Gene ID: 74140, updated on 11-Apr-2024

Summary

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Official Symbol
Tm9sf1provided by MGI
Official Full Name
transmembrane 9 superfamily member 1provided by MGI
Primary source
MGI:MGI:1921390
See related
Ensembl:ENSMUSG00000002320 AllianceGenome:MGI:1921390
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MP70; 1200014D02Rik
Summary
Predicted to be involved in protein localization to membrane. Predicted to act upstream of or within autophagy. Predicted to be located in cytoplasmic vesicle and lysosome. Predicted to be integral component of membrane. Predicted to be active in membrane. Orthologous to human TM9SF1 (transmembrane 9 superfamily member 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in colon adult (RPKM 42.3), adrenal adult (RPKM 39.5) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
14 C3; 14 28.19 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (55873422..55881263, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (55635965..55643806, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene REC8 meiotic recombination protein Neighboring gene importin 4 Neighboring gene testis-specific serine kinase 4 Neighboring gene magnesium-dependent phosphatase 1 Neighboring gene neural precursor cell expressed, developmentally down-regulated gene 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Pancreatic islet and progenitor cell surface markers with cell sorting potential. Hald J, et al. Diabetologia, 2012 Jan. PMID 21947380
  2. Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic β cells. Zhang M, et al. Mol Cell Proteomics, 2014 Nov. PMID 25044020, Free PMC Article
  3. Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia. Carninci P, et al. Genome Res, 2003 Jun. PMID 12819125, Free PMC Article
  4. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Kim H, et al. Cell, 2018 Dec 13. PMID 30550785, Free PMC Article
  5. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within autophagy IEA
Inferred from Electronic Annotation
more info
  
involved_in protein localization to membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
  
located_in lysosome IEA
Inferred from Electronic Annotation
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
transmembrane 9 superfamily member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001360063.1 → NP_001346992.1  transmembrane 9 superfamily member 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AK004754, BB610966, BE996262, BY767651
    Consensus CDS
    CCDS27122.1
    UniProtKB/Swiss-Prot
    Q3U7S4, Q8VD27, Q922J5, Q9DBU0, Q9ET29
    UniProtKB/TrEMBL
    D3Z6X7
    Related
    ENSMUSP00000002391.9, ENSMUST00000002391.15
    Conserved Domains (1) summary
    pfam02990
    Location:59 → 562
    EMP70; Endomembrane protein 70

  2. NM_028780.3 → NP_083056.2  transmembrane 9 superfamily member 1 precursor

    See identical proteins and their annotated locations for NP_083056.2

    Status: VALIDATED

    Source sequence(s)
    AK004754
    Consensus CDS
    CCDS27122.1
    UniProtKB/Swiss-Prot
    Q3U7S4, Q8VD27, Q922J5, Q9DBU0, Q9ET29
    UniProtKB/TrEMBL
    D3Z6X7
    Related
    ENSMUSP00000113782.2, ENSMUST00000122358.8
    Conserved Domains (1) summary
    pfam02990
    Location:59 → 562
    EMP70; Endomembrane protein 70

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    55873422..55881263 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030248054.2 → XP_030103914.1  transmembrane 9 superfamily member 1 isoform X1

    UniProtKB/Swiss-Prot
    Q3U7S4, Q8VD27, Q922J5, Q9DBU0, Q9ET29
    UniProtKB/TrEMBL
    D3Z6X7
    Conserved Domains (1) summary
    pfam02990
    Location:59 → 562
    EMP70; Endomembrane protein 70

  2. XM_006519616.3 → XP_006519679.1  transmembrane 9 superfamily member 1 isoform X2

    UniProtKB/TrEMBL
    D3YWH4
    Conserved Domains (1) summary
    pfam02990
    Location:59 → 406
    EMP70; Endomembrane protein 70

  3. XM_030248052.2 → XP_030103912.1  transmembrane 9 superfamily member 1 isoform X1

    UniProtKB/Swiss-Prot
    Q3U7S4, Q8VD27, Q922J5, Q9DBU0, Q9ET29
    UniProtKB/TrEMBL
    D3Z6X7
    Related
    ENSMUSP00000112893.2, ENSMUST00000120041.8
    Conserved Domains (1) summary
    pfam02990
    Location:59 → 562
    EMP70; Endomembrane protein 70

  4. XM_030248053.1 → XP_030103913.1  transmembrane 9 superfamily member 1 isoform X1

    UniProtKB/Swiss-Prot
    Q3U7S4, Q8VD27, Q922J5, Q9DBU0, Q9ET29
    UniProtKB/TrEMBL
    D3Z6X7
    Related
    ENSMUSP00000112764.2, ENSMUST00000121791.8
    Conserved Domains (1) summary
    pfam02990
    Location:59 → 562
    EMP70; Endomembrane protein 70

  5. XM_030248051.1 → XP_030103911.1  transmembrane 9 superfamily member 1 isoform X1

    UniProtKB/Swiss-Prot
    Q3U7S4, Q8VD27, Q922J5, Q9DBU0, Q9ET29
    UniProtKB/TrEMBL
    D3Z6X7
    Conserved Domains (1) summary
    pfam02990
    Location:59 → 562
    EMP70; Endomembrane protein 70

  6. XM_006519617.4 → XP_006519680.1  transmembrane 9 superfamily member 1 isoform X4

    UniProtKB/TrEMBL
    D6RGM8
    Conserved Domains (1) summary
    pfam02990
    Location:59 → 386
    EMP70; Endomembrane protein 70

  7. XM_030248055.2 → XP_030103915.1  transmembrane 9 superfamily member 1 isoform X3

    UniProtKB/TrEMBL
    D6RGM8
    Conserved Domains (1) summary
    pfam02990
    Location:59 → 387
    EMP70; Endomembrane protein 70

  8. XM_030248056.2 → XP_030103916.1  transmembrane 9 superfamily member 1 isoform X4

    UniProtKB/TrEMBL
    D6RGM8
    Related
    ENSMUSP00000115403.2, ENSMUST00000149726.8
    Conserved Domains (1) summary
    pfam02990
    Location:59 → 386
    EMP70; Endomembrane protein 70

  9. XM_036158864.1 → XP_036014757.1  transmembrane 9 superfamily member 1 isoform X3

    UniProtKB/TrEMBL
    D6RGM8
    Conserved Domains (1) summary
    pfam02990
    Location:59 → 387
    EMP70; Endomembrane protein 70

  10. XM_036158865.1 → XP_036014758.1  transmembrane 9 superfamily member 1 isoform X3

    UniProtKB/TrEMBL
    D6RGM8
    Conserved Domains (1) summary
    pfam02990
    Location:59 → 387
    EMP70; Endomembrane protein 70
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9DBU0.2 GenPept UniProtKB/Swiss-Prot:Q9DBU0

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