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Fam98c family with sequence similarity 98, member C [ Mus musculus (house mouse) ]

Gene ID: 73833, updated on 5-Mar-2024

Summary

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Official Symbol
Fam98cprovided by MGI
Official Full Name
family with sequence similarity 98, member Cprovided by MGI
Primary source
MGI:MGI:1921083
See related
Ensembl:ENSMUSG00000030590 AllianceGenome:MGI:1921083
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110006G06Rik; B230110F21Rik
Summary
Predicted to be part of tRNA-splicing ligase complex. Orthologous to human FAM98C (family with sequence similarity 98 member C). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in duodenum adult (RPKM 77.5), testis adult (RPKM 67.6) and 24 other tissues See more
Orthologs
human all
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Genomic context

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Location:
7 B1; 7 16.94 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (28851935..28855653, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (29152510..29157104, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene ryanodine receptor 1, skeletal muscle Neighboring gene predicted gene, 26604 Neighboring gene STARR-seq mESC enhancer starr_18458 Neighboring gene microRNA 1963 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:29926525-29926755 Neighboring gene RAS guanyl releasing protein 4 Neighboring gene STARR-positive B cell enhancer ABC_E9287 Neighboring gene STARR-positive B cell enhancer ABC_E8159 Neighboring gene sprouty-related EVH1 domain containing 3 Neighboring gene gametogenetin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
part_of tRNA-splicing ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
protein FAM98C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001146023.1 → NP_001139495.1  protein FAM98C

    Status: PROVISIONAL

    Source sequence(s)
    AI836081, AK138395, BY237292
    Consensus CDS
    CCDS52167.1
    UniProtKB/TrEMBL
    E9PYD1
    Related
    ENSMUSP00000131477.2, ENSMUST00000164589.9
    Conserved Domains (1) summary
    pfam10239
    Location:10 → 325
    DUF2465; Protein of unknown function (DUF2465)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    28851935..28855653 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006540393.5 → XP_006540456.1  protein FAM98C isoform X1

    Conserved Domains (1) summary
    pfam10239
    Location:10 → 288
    DUF2465; Protein of unknown function (DUF2465)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_028661.2: Suppressed sequence

    Description
    NM_028661.2: This RefSeq was permanently suppressed because it contains the wrong CDS.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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