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Tmem198b transmembrane protein 198b [ Mus musculus (house mouse) ]

Gene ID: 73827, updated on 8-Feb-2024

Summary

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Official Symbol
Tmem198bprovided by MGI
Official Full Name
transmembrane protein 198bprovided by MGI
Primary source
MGI:MGI:1921077
See related
Ensembl:ENSMUSG00000047090 AllianceGenome:MGI:1921077
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110012D08Rik
Summary
Predicted to be active in plasma membrane and vesicle membrane. Orthologous to human TMEM198B (transmembrane protein 198B (pseudogene)). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in subcutaneous fat pad adult (RPKM 11.6), limb E14.5 (RPKM 9.8) and 28 other tissues See more
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Genomic context

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Location:
10 D3; 10 77.16 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (128633958..128641255, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (128798089..128805386, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene diacylglycerol kinase, alpha Neighboring gene STARR-positive B cell enhancer ABC_E10661 Neighboring gene STARR-seq mESC enhancer starr_28300 Neighboring gene predicted gene, 31504 Neighboring gene PYM homolog 1, exon junction complex associated factor Neighboring gene ribosomal protein SA, pseudogene 2 Neighboring gene STARR-positive B cell enhancer ABC_E1817 Neighboring gene matrix metallopeptidase 19 Neighboring gene DnaJ heat shock protein family (Hsp40) member C14 Neighboring gene STARR-positive B cell enhancer ABC_E74 Neighboring gene ORM1-like 2 (S. cerevisiae) Neighboring gene SAP domain containing ribonucleoprotein Neighboring gene STARR-positive B cell enhancer ABC_E10662

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A mouse knockout library for secreted and transmembrane proteins. Tang T, et al. Nat Biotechnol, 2010 Jul. PMID 20562862
  2. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC73827

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001358266.1 → NP_001345195.1  uncharacterized protein LOC73827

    Status: VALIDATED

    Source sequence(s)
    AC131081
    Consensus CDS
    CCDS24293.1
    UniProtKB/TrEMBL
    Q8CFU0
    Conserved Domains (1) summary
    pfam13886
    Location:43 → 240
    DUF4203; Domain of unknown function (DUF4203)

  2. NM_001358267.1 → NP_001345196.1  uncharacterized protein LOC73827

    Status: VALIDATED

    Source sequence(s)
    AC131081
    Consensus CDS
    CCDS24293.1
    UniProtKB/TrEMBL
    Q8CFU0
    Conserved Domains (1) summary
    pfam13886
    Location:43 → 240
    DUF4203; Domain of unknown function (DUF4203)

  3. NM_178066.3 → NP_835167.1  uncharacterized protein LOC73827

    See identical proteins and their annotated locations for NP_835167.1

    Status: VALIDATED

    Source sequence(s)
    AC131081
    Consensus CDS
    CCDS24293.1
    UniProtKB/TrEMBL
    Q8CFU0
    Related
    ENSMUSP00000050451.8, ENSMUST00000051011.14
    Conserved Domains (1) summary
    pfam13886
    Location:43 → 240
    DUF4203; Domain of unknown function (DUF4203)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    128633958..128641255 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030245325.1 → XP_030101185.1  uncharacterized protein LOC73827 isoform X2

    Conserved Domains (1) summary
    pfam13886
    Location:43 → 240
    DUF4203; Domain of unknown function (DUF4203)

  2. XM_030245324.1 → XP_030101184.1  uncharacterized protein LOC73827 isoform X2

    Conserved Domains (1) summary
    pfam13886
    Location:43 → 240
    DUF4203; Domain of unknown function (DUF4203)

  3. XM_006514226.5 → XP_006514289.1  uncharacterized protein LOC73827 isoform X2

    Conserved Domains (1) summary
    pfam13886
    Location:43 → 240
    DUF4203; Domain of unknown function (DUF4203)

  4. XM_006514224.5 → XP_006514287.1  uncharacterized protein LOC73827 isoform X1

    See identical proteins and their annotated locations for XP_006514287.1

    UniProtKB/TrEMBL
    Q8CFU0
    Conserved Domains (1) summary
    pfam13886
    Location:43 → 240
    DUF4203; Domain of unknown function (DUF4203)

  5. XM_030245321.1 → XP_030101181.1  uncharacterized protein LOC73827 isoform X1

    UniProtKB/TrEMBL
    Q8CFU0
    Conserved Domains (1) summary
    pfam13886
    Location:43 → 240
    DUF4203; Domain of unknown function (DUF4203)

  6. XM_006514225.5 → XP_006514288.1  uncharacterized protein LOC73827 isoform X1

    See identical proteins and their annotated locations for XP_006514288.1

    UniProtKB/TrEMBL
    Q8CFU0
    Conserved Domains (1) summary
    pfam13886
    Location:43 → 240
    DUF4203; Domain of unknown function (DUF4203)

  7. XM_030245322.2 → XP_030101182.1  uncharacterized protein LOC73827 isoform X1

    UniProtKB/TrEMBL
    Q8CFU0
    Conserved Domains (1) summary
    pfam13886
    Location:43 → 240
    DUF4203; Domain of unknown function (DUF4203)

  8. XM_006514222.4 → XP_006514285.1  uncharacterized protein LOC73827 isoform X1

    See identical proteins and their annotated locations for XP_006514285.1

    UniProtKB/TrEMBL
    Q8CFU0
    Conserved Domains (1) summary
    pfam13886
    Location:43 → 240
    DUF4203; Domain of unknown function (DUF4203)
Nucleotide Protein Strain
Heading Accession and Version

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