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Poldip3 polymerase (DNA-directed), delta interacting protein 3 [ Mus musculus (house mouse) ]

Gene ID: 73826, updated on 11-Apr-2024

Summary

Official Symbol
Poldip3provided by MGI
Official Full Name
polymerase (DNA-directed), delta interacting protein 3provided by MGI
Primary source
MGI:MGI:1921076
See related
Ensembl:ENSMUSG00000041815 AllianceGenome:MGI:1921076
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
SKAR; PDIP46; mKIAA1649; 1110008P04Rik
Summary
Predicted to enable mRNA binding activity. Involved in poly(A)+ mRNA export from nucleus. Predicted to be located in cytoplasmic ribonucleoprotein granule. Predicted to be active in nuclear speck. Is expressed in several structures, including brain and retina layer. Orthologous to human POLDIP3 (DNA polymerase delta interacting protein 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 39.9), thymus adult (RPKM 34.1) and 28 other tissues See more
Orthologs
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Genomic context

See Poldip3 in Genome Data Viewer
Location:
15 E1; 15 39.4 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (83010169..83033579, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (83125968..83149378, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E3150 Neighboring gene predicted gene, 41366 Neighboring gene STARR-positive B cell enhancer ABC_E7402 Neighboring gene serine hydrolase-like Neighboring gene ribosomal RNA processing 7 homolog A Neighboring gene RNA U12, small nuclear Neighboring gene cytochrome b5 reductase 3 Neighboring gene STARR-positive B cell enhancer ABC_E4142

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • KIAA1649

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within mRNA transport IEA
Inferred from Electronic Annotation
more info
 
involved_in poly(A)+ mRNA export from nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in poly(A)+ mRNA export from nucleus IDA
Inferred from Direct Assay
more info
PubMed 
involved_in poly(A)+ mRNA export from nucleus ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of translation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within regulation of translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasmic ribonucleoprotein granule ISO
Inferred from Sequence Orthology
more info
 
is_active_in nuclear speck IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
polymerase delta-interacting protein 3
Names
S6K1 Aly/REF-like target
polymerase delta interacting protein 46

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001347082.1NP_001334011.1  polymerase delta-interacting protein 3 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AK083924, AK150130, BB711286, BC058225, BY298213
    Consensus CDS
    CCDS84183.1
    UniProtKB/TrEMBL
    Q3U8V1, Q3UDD3
    Related
    ENSMUSP00000097944.5, ENSMUST00000100375.11
  2. NM_178627.4NP_848742.1  polymerase delta-interacting protein 3 isoform 1

    See identical proteins and their annotated locations for NP_848742.1

    Status: VALIDATED

    Source sequence(s)
    AL591952
    Consensus CDS
    CCDS27697.1
    UniProtKB/Swiss-Prot
    B2FDB4, Q6PE83, Q80X99, Q8BG81, Q8CI28
    UniProtKB/TrEMBL
    Q3U8V1
    Related
    ENSMUSP00000054548.7, ENSMUST00000058793.14

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    83010169..83033579 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)