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Sh3bgrl3 SH3 domain binding glutamic acid-rich protein-like 3 [ Mus musculus (house mouse) ]

Gene ID: 73723, updated on 11-Apr-2024

Summary

Official Symbol
Sh3bgrl3provided by MGI
Official Full Name
SH3 domain binding glutamic acid-rich protein-like 3provided by MGI
Primary source
MGI:MGI:1920973
See related
Ensembl:ENSMUSG00000028843 AllianceGenome:MGI:1920973
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110004L05Rik
Summary
Predicted to enable protein-disulfide reductase activity. Predicted to be located in nuclear body. Is expressed in nervous system and thymus primordium. Orthologous to human SH3BGRL3 (SH3 domain binding glutamate rich protein like 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in spleen adult (RPKM 411.7), thymus adult (RPKM 259.5) and 27 other tissues See more
Orthologs
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Genomic context

Location:
4 D2.3; 4 66.5 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (133854717..133856044, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (134127406..134128733, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E9600 Neighboring gene STARR-positive B cell enhancer ABC_E842 Neighboring gene STARR-positive B cell enhancer ABC_E4678 Neighboring gene STARR-positive B cell enhancer ABC_E10264 Neighboring gene CD52 antigen Neighboring gene UBX domain protein 11 Neighboring gene STARR-seq mESC enhancer starr_11667 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:133677585-133677803 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:133680177-133680360 Neighboring gene centrosomal protein 85 Neighboring gene STARR-positive B cell enhancer mm9_chr4:133715471-133715771 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:133742713-133742822 Neighboring gene STARR-positive B cell enhancer ABC_E843 Neighboring gene zona pellucida like domain containing 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in ruffle membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
SH3 domain-binding glutamic acid-rich-like protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_080559.2NP_542126.1  SH3 domain-binding glutamic acid-rich-like protein 3

    See identical proteins and their annotated locations for NP_542126.1

    Status: VALIDATED

    Source sequence(s)
    AL670680
    Consensus CDS
    CCDS38910.1
    UniProtKB/Swiss-Prot
    Q91VW3
    Related
    ENSMUSP00000030651.9, ENSMUST00000030651.9
    Conserved Domains (1) summary
    pfam04908
    Location:293
    SH3BGR; SH3-binding, glutamic acid-rich protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    133854717..133856044 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)