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Itpripl1 inositol 1,4,5-triphosphate receptor interacting protein-like 1 [ Mus musculus (house mouse) ]

Gene ID: 73338, updated on 11-Apr-2024

Summary

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Official Symbol
Itpripl1provided by MGI
Official Full Name
inositol 1,4,5-triphosphate receptor interacting protein-like 1provided by MGI
Primary source
MGI:MGI:1920588
See related
Ensembl:ENSMUSG00000074825 AllianceGenome:MGI:1920588
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700041B20Rik
Summary
Predicted to be integral component of membrane. Predicted to be active in membrane. Orthologous to human ITPRIPL1 (ITPRIP like 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 9.7), mammary gland adult (RPKM 5.0) and 25 other tissues See more
Orthologs
human all
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Genomic context

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Location:
2 F1; 2 61.79 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (126980689..126985377, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (127138769..127143457, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene non-SMC condensin I complex, subunit H Neighboring gene STARR-positive B cell enhancer ABC_E3400 Neighboring gene STARR-seq mESC enhancer starr_05620 Neighboring gene predicted gene, 35347 Neighboring gene STARR-positive B cell enhancer ABC_E8792 Neighboring gene STARR-seq mESC enhancer starr_05621 Neighboring gene RIKEN cDNA 1810024B03 gene Neighboring gene STARR-positive B cell enhancer ABC_E3401 Neighboring gene small nuclear ribonucleoprotein 200 (U5)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Comparative sequence analysis of a single-gene conserved segment in mouse and human. Thomas JW, et al. Mamm Genome, 2003 Oct. PMID 14694903
  2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  3. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
  4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
inositol 1,4,5-trisphosphate receptor-interacting protein-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163527.1 → NP_001156999.1  inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 isoform a precursor

    See identical proteins and their annotated locations for NP_001156999.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    AL928590
    Consensus CDS
    CCDS50701.1
    UniProtKB/Swiss-Prot
    A1L3P2, A2ASA8, B7ZCY2
    Related
    ENSMUSP00000106016.2, ENSMUST00000110386.2
    Conserved Domains (1) summary
    pfam03281
    Location:287 → 514
    Mab-21; Mab-21 protein

  2. NM_001163528.1 → NP_001157000.1  inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 isoform a precursor

    See identical proteins and their annotated locations for NP_001157000.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    AL928590
    Consensus CDS
    CCDS50701.1
    UniProtKB/Swiss-Prot
    A1L3P2, A2ASA8, B7ZCY2
    Related
    ENSMUSP00000122289.2, ENSMUST00000154021.2
    Conserved Domains (1) summary
    pfam03281
    Location:287 → 514
    Mab-21; Mab-21 protein

  3. NM_001355634.1 → NP_001342563.1  inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 isoform b precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate internal segment compared to variant 1, that causes a frameshift. The resulting isoform (b) has a shorter and distinct C-terminus compared to isoform a.
    Source sequence(s)
    AK028913, AL928590
    Consensus CDS
    CCDS89550.1
    UniProtKB/TrEMBL
    A2ASB0
    Related
    ENSMUSP00000118487.2, ENSMUST00000132773.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    126980689..126985377 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030252117.2 → XP_030107977.1  inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 isoform X1

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A2ASA8.2 GenPept UniProtKB/Swiss-Prot:A2ASA8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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