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Lrrc69 leucine rich repeat containing 69 [ Mus musculus (house mouse) ]

Gene ID: 73314, updated on 5-Mar-2024

Summary

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Official Symbol
Lrrc69provided by MGI
Official Full Name
leucine rich repeat containing 69provided by MGI
Primary source
MGI:MGI:1920564
See related
Ensembl:ENSMUSG00000023151 AllianceGenome:MGI:1920564
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700034K16Rik
Summary
Predicted to be involved in signal transduction. Orthologous to human LRRC69 (leucine rich repeat containing 69). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 1.4) and cerebellum adult (RPKM 0.1) See more
Orthologs
human all
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Genomic context

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Location:
4 A1; 4 6.3 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (14623622..14808379, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (14623622..14808379, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene myosin, light polypeptide 6, alkali, smooth muscle and non-muscle pseudogene Neighboring gene STARR-seq mESC enhancer starr_09633 Neighboring gene STARR-seq mESC enhancer starr_09634 Neighboring gene STARR-seq mESC enhancer starr_09635 Neighboring gene solute carrier family 26, member 7 Neighboring gene STARR-seq mESC enhancer starr_09636 Neighboring gene STARR-seq mESC enhancer starr_09637 Neighboring gene STARR-positive B cell enhancer ABC_E6153 Neighboring gene OTU domain containing 6B Neighboring gene phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
leucine-rich repeat-containing protein 69

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028499.2 → NP_082775.1  leucine-rich repeat-containing protein 69

    See identical proteins and their annotated locations for NP_082775.1

    Status: PROVISIONAL

    Source sequence(s)
    AK161371
    Consensus CDS
    CCDS38696.1
    UniProtKB/Swiss-Prot
    Q9D9Q0
    Related
    ENSMUSP00000103911.2, ENSMUST00000108276.2
    Conserved Domains (3) summary
    cd00116
    Location:30 → 211
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:16 → 38
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:83 → 142
    LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    14623622..14808379 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030253831.1 → XP_030109691.1  leucine-rich repeat-containing protein 69 isoform X1

    Conserved Domains (2) summary
    COG4886
    Location:16 → 303
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:44 → 66
    LRR_RI; leucine-rich repeat [structural motif]

  2. XM_030253832.2 → XP_030109692.1  leucine-rich repeat-containing protein 69 isoform X1

    Conserved Domains (2) summary
    COG4886
    Location:16 → 303
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:44 → 66
    LRR_RI; leucine-rich repeat [structural motif]
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D9Q0.1 GenPept UniProtKB/Swiss-Prot:Q9D9Q0

Gene LinkOut

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