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Ccdc18 coiled-coil domain containing 18 [ Mus musculus (house mouse) ]

Gene ID: 73254, updated on 21-Apr-2024

Summary

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Official Symbol
Ccdc18provided by MGI
Official Full Name
coiled-coil domain containing 18provided by MGI
Primary source
MGI:MGI:1922974
See related
Ensembl:ENSMUSG00000056531 AllianceGenome:MGI:1922974
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
NY-SAR-41; 1700021E15Rik; 4932411G06Rik
Summary
Orthologous to human CCDC18 (coiled-coil domain containing 18). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in CNS E11.5 (RPKM 1.3), liver E14 (RPKM 0.9) and 12 other tissues See more
Orthologs
human all
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Genomic context

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Location:
5 F; 5 52.55 cM
Exon count:
30
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (108280583..108388378)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (108132661..108240512)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_13901 Neighboring gene STARR-seq mESC enhancer starr_13902 Neighboring gene STARR-seq mESC enhancer starr_13904 Neighboring gene metal response element binding transcription factor 2 Neighboring gene STARR-positive B cell enhancer ABC_E2166 Neighboring gene transmembrane p24 trafficking protein 5 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene 8190 Neighboring gene STARR-seq mESC enhancer starr_13907 Neighboring gene predicted gene, 54303 Neighboring gene down-regulator of transcription 1 Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class G

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous Kras(G12D). Huang J, et al. Sci Rep, 2019 Nov 20. PMID 31748650, Free PMC Article
  2. TERRA transcripts are bound by a complex array of RNA-binding proteins. López de Silanes I, et al. Nat Commun, 2010 Jun 29. PMID 20975687
  3. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  4. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC100177

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in centriolar satellite ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
coiled-coil domain-containing protein 18
Names
sarcoma antigen NY-SAR-41
NP_082757.1
XP_006535314.1
XP_006535315.1
XP_006535316.1
XP_006535318.1
XP_036021438.1
XP_036021439.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028481.1 → NP_082757.1  coiled-coil domain-containing protein 18

    See identical proteins and their annotated locations for NP_082757.1

    Status: PROVISIONAL

    Source sequence(s)
    BC082598
    Consensus CDS
    CCDS39202.1
    UniProtKB/Swiss-Prot
    Q640L5, Q8BIM9, Q8BIN1, Q9DA43
    Related
    ENSMUSP00000036507.8, ENSMUST00000047677.9
    Conserved Domains (2) summary
    COG1196
    Location:512 → 1290
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam04420
    Location:1209 → 1272
    CHD5; CHD5-like protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    108280583..108388378
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006535251.5 → XP_006535314.1  coiled-coil domain-containing protein 18 isoform X1

    See identical proteins and their annotated locations for XP_006535314.1

    Conserved Domains (2) summary
    COG1196
    Location:512 → 1290
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:115 → 888
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  2. XM_006535253.5 → XP_006535316.1  coiled-coil domain-containing protein 18 isoform X2

    Conserved Domains (2) summary
    COG1196
    Location:512 → 1244
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:115 → 888
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  3. XM_036165545.1 → XP_036021438.1  coiled-coil domain-containing protein 18 isoform X4

    Conserved Domains (1) summary
    TIGR02168
    Location:115 → 863
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  4. XM_006535255.5 → XP_006535318.1  coiled-coil domain-containing protein 18 isoform X3

    Conserved Domains (1) summary
    COG1196
    Location:114 → 903
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  5. XM_006535252.5 → XP_006535315.1  coiled-coil domain-containing protein 18 isoform X1

    See identical proteins and their annotated locations for XP_006535315.1

    Conserved Domains (2) summary
    COG1196
    Location:512 → 1290
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:115 → 888
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  6. XM_036165546.1 → XP_036021439.1  coiled-coil domain-containing protein 18 isoform X5

    Conserved Domains (1) summary
    COG1196
    Location:243 → 597
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

RNA

  1. XR_003955715.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q640L5.1 GenPept UniProtKB/Swiss-Prot:Q640L5

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