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LINC01220 long intergenic non-protein coding RNA 1220 [ Homo sapiens (human) ]

Gene ID: 731223, updated on 10-Oct-2023

Summary

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Official Symbol
LINC01220provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 1220provided by HGNC
Primary source
HGNC:HGNC:49664
See related
AllianceGenome:HGNC:49664
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
14q24.3
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (75294404..75296410)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (69503791..69505797)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (75761107..75763113)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:75745521-75746448 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:75746449-75747374 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:75747401-75747960 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:75747961-75748520 Neighboring gene ReSE screen-validated silencer GRCh37_chr14:75755848-75756032 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8743 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5944 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_36717 Neighboring gene developmental pluripotency associated 5 pseudogene 4 Neighboring gene Fos proto-oncogene, AP-1 transcription factor subunit Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_36725 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:75800727-75801226 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8744 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8745 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8746 Neighboring gene H3K27ac hESC enhancer GRCh37_chr14:75894221-75894778 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5946 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5947 Neighboring gene JDP2 antisense RNA 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:75904146-75904649 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:75905657-75906159 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8748 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:75907363-75908346 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:75918700-75919214 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:75919215-75919730 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:75919731-75920244 Neighboring gene Jun dimerization protein 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:75925593-75926141 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:75941017-75941518 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:75946817-75947707 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8750 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:75980965-75981530 Neighboring gene uncharacterized LOC105370572 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8751

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Knocking down of LINC01220 inhibits proliferation and induces apoptosis of endometrial carcinoma through silencing MAPK11. Li Y, et al. Biosci Rep, 2019 Jul 31. PMID 31123170, Free PMC Article
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Knocking down of LINC01220 inhibits proliferation and induces apoptosis of endometrial carcinoma through silencing MAPK11.
    Title: Knocking down of LINC01220 inhibits proliferation and induces apoptosis of endometrial carcinoma through silencing MAPK11.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_038421.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AF111167, BC038216, DA847937

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

    Range
    75294404..75296410
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060938.1 Alternate T2T-CHM13v2.0

    Range
    69503791..69505797
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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