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3110009E18Rik RIKEN cDNA 3110009E18 gene [ Mus musculus (house mouse) ]

Gene ID: 73103, updated on 5-Mar-2024

Summary

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Official Symbol
3110009E18Rikprovided by MGI
Official Full Name
RIKEN cDNA 3110009E18 geneprovided by MGI
Primary source
MGI:MGI:1920353
See related
Ensembl:ENSMUSG00000026388 AllianceGenome:MGI:1920353
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Orthologous to human C2orf76 (chromosome 2 open reading frame 76). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in liver adult (RPKM 17.5), CNS E14 (RPKM 2.7) and 1 other tissue See more
Orthologs
human all
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Genomic context

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Location:
1 E2.3; 1 52.66 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (120047763..120115920)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (120121082..120188190)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E10029 Neighboring gene predicted gene, 41937 Neighboring gene predicted gene, 41938 Neighboring gene STARR-positive B cell enhancer ABC_E4342 Neighboring gene diazepam binding inhibitor Neighboring gene STARR-positive B cell enhancer mm9_chr1:122050580-122050881 Neighboring gene STARR-positive B cell enhancer mm9_chr1:122093817-122094118 Neighboring gene STARR-seq mESC enhancer starr_02054 Neighboring gene STEAP family member 3 Neighboring gene STARR-seq mESC enhancer starr_02055 Neighboring gene predicted gene, 53581 Neighboring gene STARR-seq mESC enhancer starr_02056 Neighboring gene complement component 1, q subcomponent-like 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. Taniwaki T, et al. Dev Growth Differ, 2005 Apr. PMID 15840001
  2. Exchangeable gene trap using the Cre/mutated lox system. Araki K, et al. Cell Mol Biol (Noisy-le-grand), 1999 Jul. PMID 10512203
  3. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
UPF0538 protein C2orf76 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001172074.1 → NP_001165545.1  UPF0538 protein C2orf76 homolog isoform 2

    See identical proteins and their annotated locations for NP_001165545.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) skips an alternate exon in the 3' coding region resulting in a frameshift, compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AK014026, BC028767
    Consensus CDS
    CCDS48342.1
    UniProtKB/Swiss-Prot
    Q9CRW3
    Related
    ENSMUSP00000027637.7, ENSMUST00000027637.13
    Conserved Domains (1) summary
    pfam10209
    Location:8 → 78
    DUF2340; Uncharacterized conserved protein (DUF2340)

  2. NM_028439.2 → NP_082715.1  UPF0538 protein C2orf76 homolog isoform 1

    See identical proteins and their annotated locations for NP_082715.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK014026, BC028767
    Consensus CDS
    CCDS15232.1
    UniProtKB/Swiss-Prot
    Q8K163, Q9CRW3
    Related
    ENSMUSP00000108263.3, ENSMUST00000112644.9
    Conserved Domains (1) summary
    pfam10209
    Location:8 → 122
    DUF2340; Uncharacterized conserved protein (DUF2340)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    120047763..120115920
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030243151.2 → XP_030099011.1  UPF0538 protein C2orf76 homolog isoform X5

    Related
    ENSMUSP00000053335.9, ENSMUST00000056038.15
    Conserved Domains (1) summary
    pfam10209
    Location:8 → 78
    DUF2340; Uncharacterized conserved protein (DUF2340)

  2. XM_006529893.4 → XP_006529956.1  UPF0538 protein C2orf76 homolog isoform X2

    Conserved Domains (1) summary
    pfam10209
    Location:8 → 98
    DUF2340; Uncharacterized conserved protein (DUF2340)

  3. XM_017312453.3 → XP_017167942.1  UPF0538 protein C2orf76 homolog isoform X4

    Conserved Domains (1) summary
    pfam10209
    Location:14 → 84
    DUF2340; Uncharacterized conserved protein (DUF2340)

  4. XM_017312451.3 → XP_017167940.1  UPF0538 protein C2orf76 homolog isoform X1

    Conserved Domains (1) summary
    pfam10209
    Location:14 → 104
    DUF2340; Uncharacterized conserved protein (DUF2340)

  5. XM_017312452.3 → XP_017167941.1  UPF0538 protein C2orf76 homolog isoform X3

    Conserved Domains (1) summary
    pfam10209
    Location:14 → 132
    DUF2340; Uncharacterized conserved protein (DUF2340)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CRW3.2 GenPept UniProtKB/Swiss-Prot:Q9CRW3

Gene LinkOut

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