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Ppil6 peptidylprolyl isomerase (cyclophilin)-like 6 [ Mus musculus (house mouse) ]

Gene ID: 73075, updated on 3-Apr-2024

Summary

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Official Symbol
Ppil6provided by MGI
Official Full Name
peptidylprolyl isomerase (cyclophilin)-like 6provided by MGI
Primary source
MGI:MGI:1920325
See related
Ensembl:ENSMUSG00000078451 AllianceGenome:MGI:1920325
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2900084F20Rik
Summary
Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding and protein peptidyl-prolyl isomerization. Predicted to be active in cytoplasm. Orthologous to human PPIL6 (peptidylprolyl isomerase like 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis adult (RPKM 8.2), bladder adult (RPKM 5.6) and 15 other tissues See more
Orthologs
human all
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Genomic context

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Location:
10 B1- B2; 10 22.43 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (41366414..41390286)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (41490371..41514295)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:41197812-41197921 Neighboring gene predicted gene, 51797 Neighboring gene microtubule associated monooxygenase, calponin and LIM domain containing 1 Neighboring gene sphingomyelin phosphodiesterase 2, neutral Neighboring gene STARR-positive B cell enhancer ABC_E2932 Neighboring gene STARR-positive B cell enhancer ABC_E5127 Neighboring gene CD164 antigen Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:41272644-41272850 Neighboring gene coiled-coil domain containing 162 Neighboring gene predicted gene 17196

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Tissue expression patterns identify mouse cilia genes. McClintock TS, et al. Physiol Genomics, 2008 Jan 17. PMID 17971504
  2. Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray. Nishimura M, et al. DNA Res, 2004 Oct 31. PMID 15747579
  3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables peptidyl-prolyl cis-trans isomerase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein peptidyl-prolyl isomerization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
probable inactive peptidyl-prolyl cis-trans isomerase-like 6
Names
PPIase
cyclophilin-like protein PPIL6
peptidyl-prolyl cis-trans isomerase-like 6
problable inactive peptidyl-prolyl cis-trans isomerase-like 6
rotamase PPIL6
NP_001394931.1
NP_001394932.1
NP_001394933.1
NP_001394934.1
NP_001394935.1
NP_001394936.1
NP_082706.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001408002.1 → NP_001394931.1  probable inactive peptidyl-prolyl cis-trans isomerase-like 6 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC153360

  2. NM_001408003.1 → NP_001394932.1  probable inactive peptidyl-prolyl cis-trans isomerase-like 6 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC132290, AC153360

  3. NM_001408004.1 → NP_001394933.1  probable inactive peptidyl-prolyl cis-trans isomerase-like 6 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC132290, AC153360

  4. NM_001408005.1 → NP_001394934.1  probable inactive peptidyl-prolyl cis-trans isomerase-like 6 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC153360

  5. NM_001408006.1 → NP_001394935.1  probable inactive peptidyl-prolyl cis-trans isomerase-like 6 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC132290, AC153360
    Related
    ENSMUSP00000149689.2, ENSMUST00000214145.2

  6. NM_001408007.1 → NP_001394936.1  probable inactive peptidyl-prolyl cis-trans isomerase-like 6 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC132290, AC153360

  7. NM_028430.2 → NP_082706.1  probable inactive peptidyl-prolyl cis-trans isomerase-like 6 isoform 1

    See identical proteins and their annotated locations for NP_082706.1

    Status: VALIDATED

    Source sequence(s)
    AC132290, AC153360
    Consensus CDS
    CCDS48548.1
    UniProtKB/Swiss-Prot
    B2RWF7, Q9D6D8
    Related
    ENSMUSP00000101146.4, ENSMUST00000105507.5
    Conserved Domains (1) summary
    cl00197
    Location:146 → 309
    cyclophilin; cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the ...

RNA

  1. NR_176439.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC132290, AC153360

  2. NR_176440.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC132290, AC153360

  3. NR_176441.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC132290, AC153360

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    41366414..41390286
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_871442.4 RNA Sequence

  2. XR_380080.5 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D6D8.2 GenPept UniProtKB/Swiss-Prot:Q9D6D8

Gene LinkOut

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