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Fut11 fucosyltransferase 11 [ Mus musculus (house mouse) ]

Gene ID: 73068, updated on 11-Apr-2024

Summary

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Official Symbol
Fut11provided by MGI
Official Full Name
fucosyltransferase 11provided by MGI
Primary source
MGI:MGI:1920318
See related
Ensembl:ENSMUSG00000039357 AllianceGenome:MGI:1920318
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
3110009G03Rik
Summary
Predicted to enable alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in fucosylation. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Orthologous to human FUT11 (fucosyltransferase 11). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in ovary adult (RPKM 33.9), adrenal adult (RPKM 32.8) and 22 other tissues See more
Orthologs
human all
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Genomic context

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Location:
14 A3; 14 11.53 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (20745036..20750265)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (20694968..20700197)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E7297 Neighboring gene synaptopodin 2-like Neighboring gene STARR-seq mESC enhancer starr_36115 Neighboring gene SEC24 homolog C, COPII coat complex component Neighboring gene CapStarr-seq enhancer MGSCv37_chr14:21501696-21501849 Neighboring gene microRNA 6946 Neighboring gene RIKEN cDNA 6230400D17 gene Neighboring gene predicted gene, 25328 Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Dry and wet experiments reveal the significant role of FUT11 in clear cell renal cell carcinoma. Zhang P, et al. Int Immunopharmacol, 2022 Dec. PMID 36403525
  2. Comparison of human and mouse Fuc-TX and Fuc-TXI genes, and expression studies in the mouse. Baboval T, et al. Mamm Genome, 2002 Sep. PMID 12370785
  3. Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism. Roos C, et al. J Biol Chem, 2002 Feb 1. PMID 11698403
  4. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Dry and wet experiments reveal the significant role of FUT11 in clear cell renal cell carcinoma.
    Title: Dry and wet experiments reveal the significant role of FUT11 in clear cell renal cell carcinoma.
  2. amino acid sequence and expression
    Title: Comparison of human and mouse Fuc-TX and Fuc-TXI genes, and expression studies in the mouse.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables alpha-(1->3)-fucosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables fucosyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in N-glycan fucosylation ISO
Inferred from Sequence Orthology
more info
  
involved_in fucosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
alpha-(1,3)-fucosyltransferase 11
Names
fuc-TXI
fucT-XI
fucosyltransferase XI
galactoside 3-L-fucosyltransferase 11
NP_082704.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028428.2 → NP_082704.1  alpha-(1,3)-fucosyltransferase 11 precursor

    See identical proteins and their annotated locations for NP_082704.1

    Status: PROVISIONAL

    Source sequence(s)
    AC121599
    Consensus CDS
    CCDS26851.1
    UniProtKB/Swiss-Prot
    Q8BHC9, Q9CXS9
    UniProtKB/TrEMBL
    B2RRR9
    Related
    ENSMUSP00000040370.2, ENSMUST00000048016.3
    Conserved Domains (2) summary
    pfam00852
    Location:212 → 351
    Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
    pfam17039
    Location:115 → 176
    Glyco_tran_10_N; Fucosyltransferase, N-terminal

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    20745036..20750265
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BHC9.1 GenPept UniProtKB/Swiss-Prot:Q8BHC9

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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