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DHFRP2 dihydrofolate reductase pseudogene 2 [ Homo sapiens (human) ]

Gene ID: 729816, updated on 10-Oct-2023

Summary

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Official Symbol
DHFRP2provided by HGNC
Official Full Name
dihydrofolate reductase pseudogene 2provided by HGNC
Primary source
HGNC:HGNC:2863
See related
AllianceGenome:HGNC:2863
Gene type
pseudo
RefSeq status
INFERRED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
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Genomic context

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Location:
6p21.33
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (31363467..31366965, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (31219345..31222846, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (31331244..31334742, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112267902 Neighboring gene long intergenic non-protein coding RNA 2571 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr6:31304266-31305465 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:31324399-31325022 Neighboring gene microRNA 6891 Neighboring gene major histocompatibility complex, class I, B Neighboring gene RNA, U6 small nuclear 283, pseudogene Neighboring gene Sharpr-MPRA regulatory region 11702 Neighboring gene fibroblast growth factor receptor 3 pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The complete genomic sequence of 424,015 bp at the centromeric end of the HLA class I region: gene content and polymorphism. Guillaudeux T, et al. Proc Natl Acad Sci U S A, 1998 Aug 4. PMID 9689108, Free PMC Article
  2. Chromosomal organization of the human dihydrofolate reductase genes: dispersion, selective amplification, and a novel form of polymorphism. Anagnou NP, et al. Proc Natl Acad Sci U S A, 1984 Aug. PMID 6089182, Free PMC Article
  3. Chromosomal localization and racial distribution of the polymorphic human dihydrofolate reductase pseudogene (DHFRP1). Anagnou NP, et al. Am J Hum Genet, 1988 Feb. PMID 3341383, Free PMC Article
  4. Intronless human dihydrofolate reductase genes are derived from processed RNA molecules. Chen MJ, et al. Proc Natl Acad Sci U S A, 1982 Dec. PMID 6961421, Free PMC Article
  5. Identification of a susceptibility locus in STAT4 for Behçet's disease in Han Chinese in a genome-wide association study. Hou S, et al. Arthritis Rheum, 2012 Dec. PMID 23001997

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Identification of a susceptibility locus in STAT4 for Behçet's disease in Han Chinese in a genome-wide association study.
EBI GWAS Catalog
Novel associations for hypothyroidism include known autoimmune risk loci.
EBI GWAS Catalog

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

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Markers

Other Names

  • hDHFR-psi 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_001113.6 

    Range
    101..3599
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    31363467..31366965 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_2

Genomic

  1. NT_113891.3 Reference GRCh38.p14 ALT_REF_LOCI_2

    Range
    2845904..2847478 complement
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    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_6

Genomic

  1. NT_167248.2 Reference GRCh38.p14 ALT_REF_LOCI_6

    Range
    2621237..2622641 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    31219345..31222846 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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