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Fbxo47 F-box protein 47 [ Mus musculus (house mouse) ]

Gene ID: 72973, updated on 5-Mar-2024

Summary

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Official Symbol
Fbxo47provided by MGI
Official Full Name
F-box protein 47provided by MGI
Primary source
MGI:MGI:1920223
See related
Ensembl:ENSMUSG00000070336 AllianceGenome:MGI:1920223
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm1562; 2900052P03Rik
Summary
Orthologous to human FBXO47 (F-box protein 47). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 1.7), cortex adult (RPKM 0.2) and 11 other tissues See more
Orthologs
human all
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Genomic context

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See Fbxo47 in Genome Data Viewer
Location:
11 D; 11 61.14 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (97741137..97775240, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (97850311..97884386, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E7052 Neighboring gene nuclear encoded tRNA cysteine 51 (anticodon GCA) Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:97669517-97669700 Neighboring gene LIM and SH3 protein 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:97686746-97686855 Neighboring gene RIKEN cDNA B230217C12 gene Neighboring gene STARR-seq mESC enhancer starr_30642 Neighboring gene STARR-seq mESC enhancer starr_30643 Neighboring gene STARR-positive B cell enhancer ABC_E3011 Neighboring gene STARR-seq mESC enhancer starr_30644 Neighboring gene STARR-seq mESC enhancer starr_30646 Neighboring gene plexin domain containing 1 Neighboring gene STARR-seq mESC enhancer starr_30648 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:97839153-97839454 Neighboring gene predicted gene 11633 Neighboring gene STARR-positive B cell enhancer ABC_E7053 Neighboring gene STARR-positive B cell enhancer ABC_E3012 Neighboring gene nuclear encoded tRNA cysteine 55 (anticodon GCA)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Single-cell RNA-seq uncovers dynamic processes and critical regulators in mouse spermatogenesis. Chen Y, et al. Cell Res, 2018 Sep. PMID 30061742, Free PMC Article
  2. FBXO47 regulates telomere-inner nuclear envelope integration by stabilizing TRF2 during meiosis. Hua R, et al. Nucleic Acids Res, 2019 Dec 16. PMID 31724724, Free PMC Article
  3. FBXO47 is essential for preventing the synaptonemal complex from premature disassembly in mouse male meiosis. Tanno N, et al. iScience, 2022 Apr 15. PMID 35310947, Free PMC Article
  4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (5)  1 citation

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC118329

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
F-box only protein 47

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081435.2 → NP_001074904.1  F-box only protein 47 isoform 1

    See identical proteins and their annotated locations for NP_001074904.1

    Status: VALIDATED

    Source sequence(s)
    AL596446
    Consensus CDS
    CCDS36299.1
    UniProtKB/Swiss-Prot
    A2A6H3, B2RY07
    Related
    ENSMUSP00000091471.4, ENSMUST00000093939.4
    Conserved Domains (1) summary
    pfam00646
    Location:47 → 78
    F-box; F-box domain

  2. NM_001418106.1 → NP_001405035.1  F-box only protein 47 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL596446

  3. NM_001418107.1 → NP_001405036.1  F-box only protein 47 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL596446

  4. NM_001418108.1 → NP_001405037.1  F-box only protein 47 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL596446
    UniProtKB/Swiss-Prot
    A2A6H3, B2RY07

  5. NM_001418109.1 → NP_001405038.1  F-box only protein 47 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL596446

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    97741137..97775240 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036157021.1 → XP_036012914.1  F-box only protein 47 isoform X2

    Conserved Domains (1) summary
    pfam00646
    Location:47 → 78
    F-box; F-box domain

  2. XM_006534329.5 → XP_006534392.1  F-box only protein 47 isoform X1

    See identical proteins and their annotated locations for XP_006534392.1

    UniProtKB/Swiss-Prot
    A2A6H3, B2RY07
    Conserved Domains (1) summary
    pfam00646
    Location:47 → 78
    F-box; F-box domain

  3. XM_006534328.5 → XP_006534391.1  F-box only protein 47 isoform X1

    See identical proteins and their annotated locations for XP_006534391.1

    UniProtKB/Swiss-Prot
    A2A6H3, B2RY07
    Conserved Domains (1) summary
    pfam00646
    Location:47 → 78
    F-box; F-box domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A2A6H3.2 GenPept UniProtKB/Swiss-Prot:A2A6H3

Gene LinkOut

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