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ZBED3-AS1 ZBED3 antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 728723, updated on 10-Oct-2023

Summary

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Official Symbol
ZBED3-AS1provided by HGNC
Official Full Name
ZBED3 antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:44188
See related
Ensembl:ENSG00000250802 AllianceGenome:HGNC:44188
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
lnc13728
Expression
Broad expression in thyroid (RPKM 2.3), fat (RPKM 2.0) and 17 other tissues See more
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Genomic context

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Location:
5q13.3
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (77086715..77149301)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (77568346..77631222)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (76382623..76444176)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:76325887-76326466 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:76326467-76327046 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16108 Neighboring gene angiogenic factor with G-patch and FHA domains 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:76383973-76384573 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:76383370-76383972 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:76382768-76383369 Neighboring gene small nucleolar RNA, H/ACA box 47 Neighboring gene uncharacterized LOC124901008 Neighboring gene zinc finger BED-type containing 3 Neighboring gene phosphodiesterase 8B Neighboring gene Sharpr-MPRA regulatory region 15273 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:76468397-76468898 Neighboring gene high mobility group box 1 pseudogene 35 Neighboring gene aldehyde dehydrogenase 7 family member A1 pseudogene 1 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:76618089-76618784 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr5:76672412-76673040 Neighboring gene ReSE screen-validated silencer GRCh37_chr5:76752518-76752693 Neighboring gene uncharacterized LOC124901009 Neighboring gene WD repeat domain 41

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Implication of lncRNA ZBED3-AS1 downregulation in acquired resistance to Temozolomide and glycolysis in glioblastoma. Dong J, et al. Eur J Pharmacol, 2023 Jan 5. PMID 36462734
  2. Lnc13728 facilitates human mesenchymal stem cell adipogenic differentiation via positive regulation of ZBED3 and downregulation of the WNT/β-catenin pathway. Xu H, et al. Stem Cell Res Ther, 2021 Mar 12. PMID 33712067, Free PMC Article
  3. Long noncoding RNAs expression signatures in chondrogenic differentiation of human bone marrow mesenchymal stem cells. Wang L, et al. Biochem Biophys Res Commun, 2015 Jan 2. PMID 25482444
  4. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Voight BF, et al. Nat Genet, 2010 Jul. PMID 20581827, Free PMC Article
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Implication of lncRNA ZBED3-AS1 downregulation in acquired resistance to Temozolomide and glycolysis in glioblastoma.
    Title: Implication of lncRNA ZBED3-AS1 downregulation in acquired resistance to Temozolomide and glycolysis in glioblastoma.
  2. Lnc13728 facilitates human mesenchymal stem cell adipogenic differentiation via positive regulation of ZBED3 and downregulation of the WNT/beta-catenin pathway.
    Title: Lnc13728 facilitates human mesenchymal stem cell adipogenic differentiation via positive regulation of ZBED3 and downregulation of the WNT/β-catenin pathway.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

Readthrough PDE8B

Readthrough gene: PDE8B

Other Names

  • CTC-564N23.3
  • ZBED3 antisense RNA 1 (non-protein coding)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_024398.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC008581

  2. NR_182763.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC008581

  3. NR_182764.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC008581

  4. NR_182765.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC008581

  5. NR_182766.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC008581
    Related
    ENST00000643269.1

  6. NR_182767.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC008581

  7. NR_182768.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC008581

  8. NR_182769.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC008581

  9. NR_182770.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC008581

  10. NR_182771.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC008581

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    77086715..77149301
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    77568346..77631222
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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