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Zfp429 zinc finger protein 429 [ Mus musculus (house mouse) ]

Gene ID: 72807, updated on 8-Feb-2024

Summary

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Official Symbol
Zfp429provided by MGI
Official Full Name
zinc finger protein 429provided by MGI
Primary source
MGI:MGI:1920057
See related
Ensembl:ENSMUSG00000078994 AllianceGenome:MGI:1920057
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rsl2; 2810487A22Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to several human genes including ZNF429 (zinc finger protein 429). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in bladder adult (RPKM 2.4), placenta adult (RPKM 2.1) and 21 other tissues See more
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Genomic context

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Location:
13 B3; 13 34.54 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (67535695..67547963, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (67388924..67399917, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 595 Neighboring gene zinc finger protein 953 Neighboring gene STARR-positive B cell enhancer ABC_E9880 Neighboring gene predicted gene 17039 Neighboring gene zinc finger protein 456 Neighboring gene STARR-positive B cell enhancer ABC_E4075 Neighboring gene STARR-seq mESC enhancer starr_34900 Neighboring gene zinc finger protein 459 Neighboring gene STARR-seq mESC enhancer starr_34902 Neighboring gene predicted gene, 33787

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A pair of mouse KRAB zinc finger proteins modulates multiple indicators of female reproduction. Krebs CJ, et al. Biol Reprod, 2010 Apr. PMID 20042539, Free PMC Article
  2. Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2. Krebs CJ, et al. Genomics, 2005 Jun. PMID 15885501
  3. Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression. Krebs CJ, et al. Genes Dev, 2003 Nov 1. PMID 14563677, Free PMC Article
  4. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 429
Names
regulator of sex-limitation 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080941.2 → NP_001074410.2  zinc finger protein 429 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC154510
    Consensus CDS
    CCDS36714.1
    Related
    ENSMUSP00000105354.2, ENSMUST00000109732.3

  2. NM_001418851.1 → NP_001405780.1  zinc finger protein 429 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC154510

  3. NM_001418852.1 → NP_001405781.1  zinc finger protein 429 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC154510

  4. NM_001418853.1 → NP_001405782.1  zinc finger protein 429 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC154510

  5. NM_001418854.1 → NP_001405783.1  zinc finger protein 429 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC154510

  6. NM_001418855.1 → NP_001405784.1  zinc finger protein 429 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC154510

  7. NM_001418856.1 → NP_001405785.1  zinc finger protein 429 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC154510

  8. NM_001418857.1 → NP_001405786.1  zinc finger protein 429 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC154510
    Related
    ENSMUSP00000152989.2, ENSMUST00000224684.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    67535695..67547963 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030247430.2 → XP_030103290.1  zinc finger protein 429 isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:2 → 61
    KRAB; krueppel associated box
    COG5048
    Location:131 → 448
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:136 → 156
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. XM_030247429.2 → XP_030103289.1  zinc finger protein 429 isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:2 → 61
    KRAB; krueppel associated box
    COG5048
    Location:131 → 448
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:136 → 156
    ZF_C2H2; C2H2 Zn finger [structural motif]

  3. XM_036158190.1 → XP_036014083.1  zinc finger protein 429 isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:2 → 61
    KRAB; krueppel associated box
    COG5048
    Location:131 → 448
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:136 → 156
    ZF_C2H2; C2H2 Zn finger [structural motif]

  4. XM_036158189.1 → XP_036014082.1  zinc finger protein 429 isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:2 → 61
    KRAB; krueppel associated box
    COG5048
    Location:131 → 448
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:136 → 156
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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