LINC00163 long intergenic non-protein coding RNA 163 [Homo sapiens (human)] - Gene

Summary

Official Symbol: LINC00163provided by HGNC
Official Full Name: long intergenic non-protein coding RNA 163provided by HGNC
Primary source: HGNC:HGNC:33165
See related: Ensembl:ENSG00000234880 MIM:610259; AllianceGenome:HGNC:33165
Gene type: ncRNA
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: NLC1A; NLC1-A; C21orf134; NCRNA00163
Expression: Low expression observed in reference dataset See more
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Genomic context

Location:: 21q22.3

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	GRCh38.p14 (GCF_000001405.40)	21	NC_000021.9 (44989864..44994086, complement)
RS_2023_10	current	T2T-CHM13v2.0 (GCF_009914755.1)	21	NC_060945.1 (43351643..43356283, complement)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	21	NC_000021.8 (46409779..46414001, complement)

Chromosome 21 - NC_000021.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

LINC00163 expression in gastric cancer can sponge miR-183 to promote AKAP12.LINC00163/miR-183/AKAP12 axis plays an important role in the gastric invasion and metastasis.
Title: LINC00163 inhibits the invasion and metastasis of gastric cancer cells as a ceRNA by sponging miR-183 to regulate the expression of AKAP12.
NLC1-A, expressed in human hypothalamus, is considered to be a new resistance gene for human narcolepsy.
Title: Genomewide association analysis of human narcolepsy and a new resistance gene.

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Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

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Other Names

narcolepsy candidate region gene 1A
narcolepsy candidate-region 1 gene A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.