Utp14a UTP14A small subunit processome component [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Utp14aprovided by MGI
Official Full Name: UTP14A small subunit processome componentprovided by MGI
Primary source: MGI:MGI:1919804
See related: Ensembl:ENSMUSG00000063785 AllianceGenome:MGI:1919804
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: JsdX; NY-CO-16; SDCCAG16; mKIAA0266; 2700066J21Rik
Summary: Predicted to be involved in rRNA processing. Predicted to act upstream of or within ribosome biogenesis. Predicted to be located in cytosol. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Orthologous to several human genes including UTP14A (UTP14A small subunit processome component). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in CNS E11.5 (RPKM 7.3), liver E14 (RPKM 4.3) and 23 other tissues See more
Orthologs: human all
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Genomic context

Location:: X A4; X 25.59 cM

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	X	NC_000086.8 (47345811..47371326)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	X	NC_000086.7 (48256934..48282450)

Chromosome X - NC_000086.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The results shed light on the mechanism of DHX37 and the function of UTP14A in controlling its recruitment and activity during ribosome biogenesis.
Title: Molecular mechanism of the RNA helicase DHX37 and its activation by UTP14A in ribosome biogenesis.

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (3)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Process	Evidence Code	Pubs
involved_in rRNA processing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within ribosome biogenesis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytosol	ISO Inferred from Sequence Orthology more info
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of small-subunit processome	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: U3 small nucleolar RNA-associated protein 14 homolog A

Names: UTP14, U3 small nucleolar ribonucleoprotein, homolog A; jsd-like X-linked protein; juvenile spermatogonial depletion-like X-linked protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.